Human Physiology IV: Main Exam, November 2017
Mount Kenya University · Department of Dental Sciences · Diploma in Community Oral Health · DDS2111
Human Physiology IV past paper from Mount Kenya University 2017-2018 with model answers for dds2111 unit.
Instructions: ANSWER ALL QUESTIONS IN SECTION A AND ANY OTHER TWO IN SECTION B
SECTION A (30 marks)
1. Define the following terms:
- a) Thermo regulationModel answer
- Thermoregulation: The physiological processes that maintain core body temperature within a narrow optimal range despite external temperature changes.
- b) FeverModel answer
- Fever: A regulated rise in body temperature above the normal set point, usually in response to infection or inflammation.
- c) Taste budsModel answer
- Taste buds: Specialized sensory papillae on the tongue containing gustatory receptor cells that detect sweet, salty, sour, bitter and umami stimuli.
- d) HyperpyrexiaModel answer
- Hyperpyrexia: An extreme fever, typically a core temperature exceeding 41.5 °C (106.7 °F), requiring urgent medical intervention.
- e) Metabolic RateModel answer
- Metabolic Rate: The amount of energy expended by the body per unit time, usually expressed as basal metabolic rate (BMR) in kcal/day.
2. Draw a well labeled diagram showing taste zone.
- Diagram description: Show a lateral view of the tongue with the circumvallate, foliate, and fungiform papillae highlighted as the main taste zones. Include labels for:
- Circumvallate papillae (posterior tongue)
- Foliate papillae (lateral margins)
- Fungiform papillae (anterior tip and dorsum)
- Taste bud clusters within each papilla
- Lingual epithelium surface
- Glossopharyngeal nerve (IX) and facial nerve (VII) pathways indicated.
3. Classify hypothermia.
- Hypothermia classification
- Mild: 32–35 °C (98.6–95 °F)
- Moderate: 28–32 °C (82.4–89.6 °F)
- Severe: <28 °C (82.4 °F)
4. Briefly explain how shivering takes place in heat production.
- Shivering mechanism
- Trigger: Hypothalamic thermoregulatory centre senses ↓core temperature
- Signal: Sympathetic output to skeletal muscle
- Action: Rapid, involuntary muscle contractions
- Heat production: Mechanical work converted to metabolic heat
- Feedback: Rising temperature reduces shivering intensity
5. Explain the function of olfactory cilia of the nose.
- Olfactory cilia function
- Detection: Bind odorant molecules in mucus
- Signal transduction: Activate olfactory receptor neurons
- Transmission: Send impulses via olfactory nerve to brain
- Perception: Odor identification and discrimination
6. Draw a well labeled diagram showing parts of the skin.
- Diagram description
- Layers: Epidermis, Dermis, Hypodermis
- Epidermis: Stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, stratum basale
- Dermis: Papillary dermis, Reticular dermis
- Hypodermis: Subcutaneous fat
- Other structures: Hair follicle, sebaceous gland, sweat gland, blood vessels, nerves
7. Write short notes on apocrine sweat glands.
- Apocrine sweat glands
- Location: Axillae, anogenital region, areola
- Secretion: Thick, milky fluid rich in proteins
- Trigger: Sympathetic cholinergic stimulation
- Function: Thermoregulation and pheromone release
- Odor: Bacterial breakdown causes body odor
8. Briefly explain two parts of the ear, indicating their function.
- External auditory canal
- Function: Conducts sound waves to tympanic membrane
- Middle ear
- Function: Amplifies and transmits vibrations via ossicles to inner ear
SECTION B (40 marks)
1. Discuss functions of the skin.
- Barrier protection: Prevents entry of pathogens, chemicals and physical trauma.
- Regulation of body temperature: Through sweating and vasodilation/vasoconstriction.
- Sensory reception: Contains mechanoreceptors, thermoreceptors and nociceptors for touch, pressure, temperature and pain.
- Excretion: Eliminates waste products such as urea and salts via sweat.
- Vitamin D synthesis: UV‑B radiation converts 7‑dehydrocholesterol to pre‑vitamin D3.
- Water balance: Controls transepidermal water loss and re‑absorption.
- Immune function: Langerhans cells detect antigens and initiate immune responses.
- Aesthetic & communication role: Skin colour, texture and hair convey social and health information.
2. Body temperature regulation occurs in two way; heat production and heat loss, disc
- Heat production: Metabolic activity (basal metabolism, muscle shivering) generates heat.
- Heat loss:
- Radiation: Emission of infrared energy from skin surface.
- Conduction: Direct transfer of heat to cooler objects in contact.
- Convection: Air or water flow removes heat from skin.
- Evaporation: Sweat evaporation absorbs latent heat, cooling the body.
- Vasomotor control: Vasodilation increases heat loss; vasoconstriction reduces it.
- Behavioral responses: Changing clothing, seeking shade or warmth, adjusting activity level.
3. Explain the skin appendages.
- Hair: Provides insulation, sensory function and protection; consists of a shaft, follicle and associated sebaceous gland.
- Nails: Protect distal phalanges, aid fine manipulation; composed of hard keratin plates.
- Sweat glands:
- Eccrine glands: Widely distributed, produce watery sweat for thermoregulation.
- Apocrine glands: Located in axillae and groin, secrete viscous fluid that contributes to body odor.
- Sebaceous glands: Secrete sebum onto the skin surface, lubricating hair and skin and providing antimicrobial lipids.
- Sensory receptors: Merkel cells, Meissner’s corpuscles, Pacinian corpuscles and free nerve endings embedded in the dermis and epidermis.
- Arrector pili muscles: Small smooth muscles attached to hair follicles that cause goose‑bumps when contracted.