Practice 49 MCQs on Parasitology Examination with OmpathStudy. Built for Kenyan medical and health students to revise key concepts and prepare for exams.
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Q1. Which of the following is the least site for formation of hydatid cyst?
- Bones
- Liver
- Lungs
- Brain
- None of the above
- Brain
Answer: Brain
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Q2. Which of the following meals is BEST advisable to be taken with albendazole?
- Carbohydrates
- Proteins
- Vitamins
- Fats
- All of the above
- Fats
Answer: Fats
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Q3. Which of the following is an armed tapeworm?
- Broad tapeworm
- Pork tapeworm
- Beef tapeworm
- Dwarf tapeworm
- All of the above
- Pork tapeworm
Answer: Pork tapeworm
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Q4. Which of the following medication is given based on body weight in treatment of broad tapeworm?
- Niclosamide
- Praziquantel
- Metriphonate
- Albendazole
- All of the above
- Praziquantel
Answer: Praziquantel
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Q5. Each of the following statements concerning Ascaris lumbricoides is correct except?
- *Ascaris lumbricoides* is one of the largest nematode
- Both dogs and cats are intermediate host of *Ascaris lumbricoides*
- *Ascaris lumbricoides* can cause pneumonia
- *Ascaris lumbricoides* is transmitted by ingestion of eggs
- None of the above
- Both dogs and cats are intermediate host of *Ascaris lumbricoides *
Answer: Both dogs and cats are intermediate host of *Ascaris lumbricoides*
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Q6. The human infective stage of Taenia solium is?
- Plerocercoid
- Procercoid
- Cysticercus bovis
- Cysticercus cellulosae
- Cercariae
- Cysticercus cellulosae
Answer: Cysticercus cellulosae
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Q7. In which muscles are hexacanth filtered out in the intermediate hosts?
- Smooth muscles
- Striated muscles
- Cardiac muscles
- All of the above
- Striated muscles
Answer: Striated muscles
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Q8. Which part of the human body is not inhabited by the larvae in cysticercosis?
- Brain
- Liver
- Lung
- Kidney
- None of the above
- Liver
Answer: Liver
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Q9. Which of the following parasites cause sparganosis?
- *Ancylostoma braziliense*
- *Taenia saginata*
- *Strongyloides stercoralis*
- *Toxocara canis*
- *Spirometra theileri *
- *Spirometra theileri *
Answer: *Spirometra theileri *
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Q10. Which parasite is best diagnosed using lymphatic fluid?
- *Ascaris lumbricoides*
- *Wuchereria bancrofti*
- *Enterobium vermicularis*
- *Taenia multiceps*
- All of the above
- *Wuchereria bancrofti *
Answer: *Wuchereria bancrofti*
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Q11. Which of the following tapeworm infections will require prescription with clonazepam? (Select all)
- Broad tapeworm
- Pork tapeworm
- Beef tapeworm
- Dwarf tapeworm
- All of the above
- Pork tapeworm
Answer: Pork tapeworm
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Q12. Which parasite results into micropthalmia condition?
- *Diphyllobothrium latum*
- *Toxoplasma gondii*
- *Strongyloides stercoralis*
- *Toxocara canis*
- *Enterobium vermicularis *
- *Toxocara canis *
Answer: *Toxocara canis*
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Q13. Which of the following medication is given after a light breakfast?
- Niclosamide
- Praziquantel
- Metriphonate
- Albendazole
- All of the above
- Praziquantel
Answer: Praziquantel
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Q14. Albendazole mode of action include interference with?
- ATP production
- Glucose uptake
- Water absorption
- Membrane permeability
- RNA synthesis
- Glucose uptake
Answer: Glucose uptake
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Q15. Which of the following medication is contraindicated in thrombocytopenia taenia infected patients?
- Niclosamide
- Praziquantel
- Metriphonate
- Albendazole
- All of the above
- Praziquantel
Answer: Praziquantel
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Q16. Swimmer's itch is produced by?
- *Necator americanus*
- *Schistosoma haematobium*
- *Enterobium vermicularis*
- *Diphyllobothrium latum*
- All of the above
- *Schistosoma haematobium *
Answer: *Schistosoma haematobium*
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Q17. Which one is associated with nocturnal pruritis ani?
- *Necator americanus*
- *Enterobium vermicularis*
- *Ascaris lumbricoides*
- *Diphyllobothrium latum*
- None of the above
- *Enterobium vermicularis *
Answer: *Enterobium vermicularis*
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Q18. Which of the following is ciliated?
- Rediae
- Cercariae
- Coracidium
- Filariform
- Microfilariae
- Coracidium
Answer: Coracidium
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Q19. National Institute of Health (NIH) tape technique is used for diagnosis of?
- *Ancylostoma braziliense*
- *Enterobium vermicularis*
- *Strongyloides stercoralis*
- *Toxocara canis*
- *Diphyllobothrium latum *
- *Enterobium vermicularis *
Answer: *Enterobium vermicularis*
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Q20. Which of the following is a false tapeworm?
- *Ancylostoma braziliense*
- *Enterobium vermicularis*
- *Strongyloides stercoralis*
- *Toxocara canis*
- *Diphyllobothrium latum *
- *Diphyllobothrium latum *
Answer: *Diphyllobothrium latum *
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Q21. Which parasite can cause erosion of bones?
- *Ascaris lumbricoides*
- *Echinococcus granulosus*
- *Gnathostoma spinigerum*
- *Taenia multiceps*
- All of the above
- All of the above
Answer: All of the above
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Q22. Prolonged coughing and chest pains can be associated with?
- *Echinostoma ilocanum*
- *Paragonimus westermanii*
- *Fasciolopsis buski*
- *Clonorchis sinensis*
- *Schistosoma haematobium *
- *Paragonimus westermanii *
Answer: *Paragonimus westermanii*
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Q23. Bothriocephalus anaemia is due to
- *Ancylostoma braziliense*
- *Taenia saginata*
- *Strongyloides stercoralis*
- *Toxocara canis*
- *Diphyllobothrium latum *
- *Diphyllobothrium latum *
Answer: *Diphyllobothrium latum *
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Q24. Which of the following medication is given based on age in treatment of broad tapeworm?
- Niclosamide
- Praziquantel
- Metriphonate
- Albendazole
- All of the above
- Niclosamide
Answer: Niclosamide
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Q25. Squamous carcinoma of the bladder is associated with which stage?
- Adult
- Egg
- Cercarial
- Metacercaria
- All of the above
- Cercarial
Answer: Cercarial
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Q26. Which of the following parasites is associated with achlorhydria?
- *Amoeba* species
- *Trichomonas* species
- *Giardia* species
- *Leishmania* species
- *Giardia* species
Answer: *Giardia* species
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Q27. Metronidazole parasite site of target is?
- RNA
- DNA
- Ribosomes
- Cytoskeleton
- DNA
Answer: DNA
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Q28. Which of the following parasites is associated with pyosalpingitis?
- *Amoeba* species
- *Trichomonas* species
- *Giardia* species
- *Leishmania* species
- *Trichomonas* species
Answer: *Trichomonas* species
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Q29. Which of the following biomolecules helps in the survival of both Leishmania and Plasmodium parasites?
- Lpg
- Gpi
- Gp63
- G6pd
- All of the above
- All of the above
Answer: All of the above
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Q30. Which of the following medication is administered IV?
- Artesunate
- Pentamidine
- Arthemeter
- Emetine
- Paromomycin
- Artesunate
Answer: Artesunate
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Q31. Which of the following medicines is antagonist to folic acid?
- Sulfadiazine
- Pentamidine
- Arthemeter
- Fansidar
- Paromomycin
- Fansidar (*Fansidar is a combination of sulfadoxine and pyrimethamine—both folate antagonists.*)
Answer: Fansidar
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Q32. Which drug targets the A site of the ribosomes?
- Pyrimethamine
- Pentamidine
- Benzimidazoles
- Miltefosine
- Paromomycin
- Paromomycin (*Paromomycin binds to the A site of the 30S ribosomal subunit, disrupting protein synthesis.*)
Answer: Paromomycin
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Q33. Which drug targets the dihydropteroate synthase?
- Pyrimethamine
- Sulfadoxine
- Benzimidazoles
- Miltefosine
- Paromomycin
- Sulfadoxine (*Sulfadoxine inhibits dihydropteroate synthase in folate synthesis pathway.*)
Answer: Sulfadoxine
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Q34. Which drug targets the dihydrofolate reductase?
- Pyrimethamine
- Sulfadiazine
- Benzimidazoles
- Nifurtimox
- Sulfadoxine
- Pyrimethamine (*Pyrimethamine is a selective inhibitor of protozoan dihydrofolate reductase.*)
Answer: Pyrimethamine
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Q35. Which drug targets the vicynyl sulfhydryl groups of pyruvate kinase?
- Pyrimethamine
- Sulfadiazine
- Meglumine antimonate
- Melarsoprol
- Sulfadoxine
- Melarsoprol (*Melarsoprol reacts with vicinal thiol groups of enzymes like pyruvate kinase, disrupting parasite metabolism.*)
Answer: Melarsoprol
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Q36. Which drug targets the ornithine decarboxylase?
- Eflornithine
- Sulfadiazine
- Eflornithine (*Eflornithine irreversibly inhibits ornithine decarboxylase, crucial in polyamine synthesis in trypanosomes.*)
Answer: Eflornithine
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Q37. Mucoid stools are associated with?
- Schistosoma japonicum
- Giardia lamblia
- Schistosoma mansoni
- Entamoeba histolytica
- Fasciola hepatica
- Entamoeba histolytica (*Causes amoebic dysentery with bloody, mucoid stools.*)
Answer: Entamoeba histolytica
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Q38. Each of the following statements concerning Malaria is correct except
- The female anopheles mosquito is the vector
- The principal site of gametocyte formation is the human gastrointestinal tract
- Release of merozoites from red blood cells causes fever and chills
- Early infection, sporozoites enter hepatocytes
- None of the above
- The principal site of gametocyte formation is the human gastrointestinal tract (*Gametocytes form in red blood cells, not the GI tract.*)
Answer: The principal site of gametocyte formation is the human gastrointestinal tract
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Q39. Which of the following lesions progress to ulcerate?
- Nodular lesions
- Diffuse cutaneous
- Erythematous patches
- Depigmented macules
- All of the above
- Nodular lesions (*Nodular lesions, such as those in cutaneous leishmaniasis, can ulcerate.*)
Answer: Nodular lesions
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Q40. Which of the following causes both visceral and cutaneous leishmaniasis?
- L. donovani
- L. infantum
- L. chagasi
- L. braziliensis
- L. aethiopica
- L. aethiopica (*L. aethiopica is primarily cutaneous but can rarely cause visceral symptoms.*)
Answer: L. aethiopica
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Q41. Which one of the following causes espundia?
- L. tropica
- L. infantum
- L. chagasi
- L. braziliensis
- L. aethiopica
- L. braziliensis (*L. braziliensis causes mucocutaneous leishmaniasis, also known as espundia.*)
Answer: L. braziliensis
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Q42. Which one of the following causes chiclero's ulcers?
- L. mexicana
- L. infantum
- L. chagasi
- L. braziliensis
- L. major
- L. mexicana (*Chiclero’s ulcer is caused by L. mexicana, typically affecting the ear.*)
Answer: L. mexicana
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Q43. Which of the following lesions do not respond to chemotherapy?
- Oriental sores
- Delhi boil
- Zoonotic rural
- Diffuse cutaneous
- Leishmaniasis recidivans
- Leishmaniasis recidivans (*Leishmaniasis recidivans is a chronic form that responds poorly to treatment.*)
Answer: Leishmaniasis recidivans
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Q44. How many dose(s) is/are recommended for RTS, S/AS01?
- 4 (*The RTS,S/AS01 malaria vaccine is given in 4 doses.*)
Answer: 4 (*The RTS,S/AS01 malaria vaccine is given in 4 doses.*)
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Q45. Which of the following asymptomatic infections should not be treated?
- Amoebiasis
- Giardiasis
- Trichomoniasis
- Trypanosomiasis
- Trypanosomiasis (*Due to its severity and progression, trypanosomiasis is treated even if asymptomatic.* However, asymptomatic giardiasis may not be treated in endemic areas.) Correct answer (based on standard protocols):
- Amoebiasis is typically treated Best
- Giardiasis , in endemic cases(*Please confirm local guidelines for clarity*)
Answer: Trypanosomiasis
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Q46. Which of the following medications should NOT be given to 1st trimester of pregnancy?
- Furazolidone
- Paromomycin
- Tinidazole
- Iodoquinol
- Tinidazole (*Tinidazole is contraindicated in the first trimester due to potential teratogenic effects.*)
Answer: Tinidazole
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Q47. Which of the following exists only as a trophozoite?
- histolytica
- T. hominis
- G. intestinalis
- None of the above
- T. hominis (*Trichomonas hominis exists only in the trophozoite form.*)
Answer: G. intestinalis
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Q48. Which of the following medication should NOT be given to children <1 month old?
- Furazolidone
- Paromomycin
- Tinidazole
- Nitazoxanide
- Nitazoxanide (*Nitazoxanide is not recommended for infants under 1 year, particularly under 1 month.*)
Answer: Nitazoxanide
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Q49. Which of the following drugs targets the A site of parasite ribosome?
- Furazolidone
- Paromomycin
- Tinidazole
- Diloxanide furoate
- Paromomycin (*It binds to the A site of the 30S ribosomal subunit, disrupting protein synthesis in parasites.*)
Answer: Paromomycin