Introduction to Psychopathology

Year 4 psychiatry presentation notes: the language of abnormal mental experience: the mental state domains, form versus content of thought, delusion versus hallucination versus illusion, mood versus affect, insight.

Class presentation 2: the language psychiatrists use to describe abnormalities of mental experience and behaviour. Ten questions plus the take-home question. Plan 15–20 minutes.

Purpose: understand the language psychiatrists use to describe abnormalities of mental experience and behaviour.

1. What is psychopathology?

  • Psychopathology is the study of abnormal mental experience and behaviour: the description (what is abnormal and how), and the explanation (why it occurs).
  • Descriptive psychopathology (Karl Jaspers) records exactly what the patient experiences (phenomenology) and what the examiner observes, without first interpreting it as a disorder.
  • It is the vocabulary of psychiatry: the shared words that let one clinician understand another's examination.

2. Why must a medical student learn it before the disorders?

  • Every psychiatric diagnosis is built from these symptoms and signs. You cannot understand "schizophrenia" without knowing hallucinations, delusions and thought disorder.
  • It lets you take a precise history and mental state examination (MSE) and write it so others can use it.
  • It prevents mislabelling: knowing what a delusion is stops you calling every strange belief a delusion.
  • It is how psychiatry communicates, as signs and symptoms do in other specialties.

3. Major domains of mental functioning examined

The mental state examination follows these domains:

  1. Appearance and behaviour
  2. Speech
  3. Mood and affect
  4. Thought (form, content, possession)
  5. Perception
  6. Cognition (orientation, attention, memory, executive function)
  7. Insight and judgement

(Risk to self and others is assessed throughout.)

4. Abnormalities in each domain

Appearance and behaviour

  • Self-neglect, bizarre or inappropriate dress, odd posture.
  • Psychomotor agitation or retardation; overactivity and disinhibition (mania).
  • Catatonia: stupor, mutism, posturing, waxy flexibility, negativism, stereotypies, echolalia and echopraxia.
  • Tics, tremor, akathisia (inner restlessness from antipsychotics), mannerisms, eye contact, rapport.

Speech (rate, amount, volume, tone)

  • Pressured speech (mania); poverty of speech and mutism (depression, schizophrenia); slow, monotonous (depression); dysarthria or slurring (neurological, intoxication).

Mood and affect

  • Mood: depressed, elated, euphoric, irritable, anxious, anhedonia.
  • Affect: blunted, flat, restricted, labile, incongruent, inappropriate.

Thought

  • Form: flight of ideas, loosening of associations (derailment), tangentiality, circumstantiality, thought block, neologisms, word salad, perseveration.
  • Content: delusions, overvalued ideas, obsessions, phobias, preoccupations, suicidal or homicidal ideas.
  • Possession (passivity phenomena): thought insertion, withdrawal, broadcasting.

Perception

  • Hallucinations (auditory, visual, olfactory, gustatory, tactile), illusions, pseudo-hallucinations, depersonalisation and derealisation.

Cognition

  • Disorientation, impaired attention, memory loss, poor executive function, impaired abstraction, intellectual disability. Acute, fluctuating: delirium. Gradual, progressive: dementia.

Insight and judgement

  • Insight: from complete denial of illness, through awareness with blame on others or external factors, to true emotional insight.
  • Judgement: impaired decisions about treatment, safety, money, relationships.

5. Form versus content of thought

FormContent
QuestionHow does the person think and speak?What is the person thinking about?
ConcernsFlow, speed and connection of ideasBeliefs, preoccupations, ideas
AbnormalitiesFlight of ideas, derailment, thought block, word saladDelusions, obsessions, overvalued ideas, suicidal thoughts
Typical exampleRapid jumping between topics with rhyming (mania)"My neighbours are poisoning my food"

The same patient can have normal form with abnormal content (a patient with a well-organised delusion) or the reverse.

6. Delusion, hallucination and illusion

DelusionHallucinationIllusion
Disorder ofThought (belief)PerceptionPerception
DefinitionA fixed, false belief, held with unshakeable conviction, out of keeping with the person's education and culture, not changed by evidenceA perception without an external stimulusA misinterpretation of a real stimulus
Example"The president is sending me secret messages"Hearing a voice commenting when nobody is presentSeeing a coat on a door as a person in the dark
Seen inSchizophrenia, mania, psychotic depression, deliriumSchizophrenia, delirium, substance use, epilepsyDelirium, anxiety, fatigue; can be normal

Types of delusion: persecutory, grandiose, delusion of reference, jealousy (Othello), erotomanic, somatic, guilt, and nihilistic (Cotard). Primary delusions arise "out of the blue"; secondary delusions follow another experience (for example mood). Always check the cultural and religious context before calling a belief a delusion.

7. Mood versus affect

  • Mood: the sustained emotional state the patient reports (the climate).
  • Affect: the observed emotional expression (the weather).
  • Example: a patient says "I'm fine" (mood) but looks tearful and flat (affect).

8. Insight

  • Insight is the patient's awareness and understanding that they have a mental illness, that their symptoms are part of it, and that treatment is needed.
  • Three components: recognising the illness, relabelling unusual experiences as symptoms, and accepting treatment.
  • It is a continuum, not yes or no, and it changes over the course of illness.
  • Good insight predicts better adherence and outcome; poor insight is typical of mania and psychosis.

9. Why describe psychopathology before interpreting it?

  • Avoids premature closure: the first diagnosis you think of may be wrong.
  • Lets you separate evidence from conclusion so others can check your reasoning.
  • The same symptom occurs in many disorders (hallucinations in schizophrenia, delirium, substance use, epilepsy).
  • Prevents cultural error: a belief or experience may be normal in the patient's culture.
  • Provides a record that stays useful even if the diagnosis changes.
  • Method: observe and describe → name the phenomena → consider the syndrome → consider the diagnosis.

10. Clinical application: describe, do not diagnose

Patient statement: "The people next door talk about me all day. I hear them through the wall, saying I am dirty. Last night a machine put thoughts into my head and now they are not mine. I've stopped eating because they poison my food. I am not sick; I just need them to stop."

Description of the psychopathology (no diagnosis):

  • Perception: auditory hallucinations, third-person, derogatory.
  • Thought possession: thought insertion (a passivity phenomenon).
  • Thought content: persecutory delusions (poisoning) leading to food refusal.
  • Insight: absent: denies illness ("I am not sick").
  • Behaviour: reduced eating (secondary to the delusion).
  • Still needed: mood and affect, speech and form of thought, cognition, risk, substance use, duration. Only then consider the syndrome and the diagnosis.

Take-home question: what did you observe or establish, and what conclusion are you making from it?

  • Observed (data): what you saw, heard and were told, in the patient's own words and your own description.
  • Concluded (interpretation): what you think it means (a delusion, a hallucination, a syndrome, a diagnosis).
  • Keep them separate. Write "the patient says he hears voices commenting on him", then "this is consistent with third-person auditory hallucinations", and only then "which raises a psychotic disorder".
  • Observations are facts you can defend; conclusions are hypotheses you must test.

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Compiled by Abongo Davis · Ompath Study · shared for MBChB students at Mount Kenya University and other universities.