Integrated case paper: Medicine, Surgery, Gynaecology and Paediatrics (160 marks)

MKU integrated case paper: hypothyroidism and thyroid surgery, infertility and IVF, term premature rupture of membranes, neonatal sepsis and separation anxiety disorder, with answers.

Paper details

  • Paper: "Case on IMED, SURG and GYN and PEDS", 160 marks. The scan has no printed date or unit code, so it is filed as undated.
  • Questions: 6 case questions (hypothyroidism and thyroid surgery, infertility, IVF, term rupture of membranes, neonatal sepsis, separation anxiety disorder).
  • Answers: written by OmpathStudy for revision. They are not the official MKU marking scheme.
  • Topics tested: hypothyroidism, thyroid surgery and anatomy, infertility work-up and treatment, IVF, premature rupture of membranes, neonatal sepsis, childhood anxiety disorders.

Case 1 (50 marks). A 50-year-old housewife with 20 lb weight gain in a year, fatigue, dizziness, memory loss, slow speech, a deepening voice, dry skin, constipation and cold intolerance. Temperature 96.8 °F, pulse 58 regular, BP 110/60, moderately obese, slow speech, puffy face, pale cool dry thick skin, thyroid not palpable, delayed reflex relaxation

(a) Likely diagnosis (1 mark)

(b) Symptoms that point to it (5 marks)

(c) Supporting physical findings (5 marks)

(d) Additional history and examination to help diagnosis (10 marks)

(e) Tests to confirm (5 marks)

(f) Treatment and drug mechanism (10 marks)

(g) Types of thyroid surgery (5 marks)

(h) Complications of surgery (5 marks)

(i) Structures in the same fascial plane as the thyroid (4 marks)


Case 2 (25 marks). A patient with infertility: outline your management before diagnosis


Case 3. If she is considered for IVF

Preconception care (5 marks)

Risks of IVF


Case 4 (5 marks each). After IVF, at 37 weeks she has a constant trickle of clear fluid for 8 hours, scanty first-trimester bleeding, reassuring fetal wellbeing, no contractions, soft abdomen, afebrile

At 37 completed weeks this is premature rupture of membranes at term (PROM). (Rupture before 37 weeks is PPROM.)

(a) How to confirm

(b) Other diagnoses to consider

(c) Complications

(d) Treatment plan


Case 5 (30 marks). A neonate born by caesarean section develops fever, tachypnoea, tachycardia and crepitations at 42 hours, with raised procalcitonin and CRP: neonatal sepsis

(a) Define early- and late-onset neonatal sepsis (2 marks)

(b) Risks and aetiology (8 marks)

(c) Stepwise diagnosis (10 marks)

(d) Treatment of a 2.8 kg baby who cannot feed (10 marks)


Case 6 (30 marks). At 4 years, Gathei is very anxious when her big brother leaves for school, refuses to feed, refuses day care if he is not taking her, and has tummy aches when sleeping in a different room from him

(a) Most likely diagnosis, with DSM-5 criteria (10 marks)

(b) Risk factors for anxiety disorders (5 marks)

(c) Management (10 marks)

(d) Three drugs and their mechanism (5 marks)

Model answers are on the page for subscribers.

Compiled by Abongo Davis · Ompath Study · shared for MBChB students at Mount Kenya University and other universities.