Acute Chest Syndrome

Also written as ACS.

Acute chest syndrome needs a cephalosporin plus a macrolide to cover typical and atypical organisms.

What our notes say

• Acute chest syndrome needs a cephalosporin plus a macrolide to cover typical and atypical organisms. (Paediatrics Senior Clerkship end of 2nd semester exam: 4 October 2021, 50 MCQs)
• Sickle Cell Disease: Can present with acute chest syndrome, which may involve pericardial inflammation or effusion. (Pericarditis, effusion and tamponade)
• | Obstructive | Extracardiac flow obstruction | Pericardial tamponade (TB pericarditis), tension pneumothorax, pulmonary embolism, sickle cell acute chest syndrome | (Shock and cardiovascular emergencies)
• Sickle Cell Disease: Precipitates hypovolemic shock (splenic sequestration crisis in children) or obstructive shock (acute chest syndrome with cor pulmonale). (Shock and cardiovascular emergencies)
• | Chest findings (crepitations, tachypnoea) | Acute chest syndrome – pulmonary vaso‑occlusion, infection, or fat embolism. | (Sickle cell disease)
• | Acute chest syndrome | Chest pain, cough, hypoxia, new infiltrate | CXR infiltrates, hypoxia, may coexist with vaso‑occlusive pain | (Sickle cell disease)

Study material on Acute Chest Syndrome

• Sickle cell disease
• Sickle Cell Disease: Pathology, Genetics & Mechanisms

Related topics

• Elevated Jugular Venous Pressure
• Avascular Necrosis
• Haemophilia
• Sickle Cell Disease
• Haemoglobin
• Pericardium
• Inheritance Patterns
• Haemolytic Anaemia
• Anaemia
• Stroke