Acute Hemolytic Transfusion Reaction

Also written as AHTR.

| Acute hemolytic transfusion reaction (AHTR) | Fever, flank pain, dark urine, hypotension, rapid fall in Hb, positive direct Coombs | Immediate onset, evidence of intravascular hemolysis, complement‑mediated, not primarily respiratory. |

What our notes say

• | Acute hemolytic transfusion reaction (AHTR) | Fever, flank pain, dark urine, hypotension, rapid fall in Hb, positive direct Coombs | Immediate onset, evidence of intravascular hemolysis, complement‑mediated, not primarily respiratory. | (Blood transfusion and reactions)
• | Acute hemolytic transfusion reaction | Fever, flank pain, ↓Hb, ↑LDH, ↓haptoglobin, positive DAT, hemoglobinuria, timing ≤ 4 h | Mild – symptoms controlled with fluids; Moderate – hypotension, renal impairment; Severe – shock, disseminated intravascular coagulation, death. | (Blood transfusion and reactions)

Study material on Acute Hemolytic Transfusion Reaction

• Blood transfusion and reactions

Practice questions on Acute Hemolytic Transfusion Reaction

Which of the following is a sign of an acute hemolytic transfusion reaction?

• Fever and chills
• Low blood pressure
• Dark urine
• All of the above

Answer: D. Acute hemolytic transfusion reactions can manifest with a range of symptoms including fever, chills, hypotension (low blood pressure), back pain, and dark or red-colored urine (hemoglobinuria).

Related topics

• Anaphylaxis
• Septic Shock
• Pulmonary Oedema
• Respiratory Failure
• Blood Transfusion
• Complications and Prognosis
• Renal Function
• Red Blood Cell
• Sickle Cell Disease
• Differential Diagnosis