Cryptococcosis

Flucytosine and fluconazole — both used to treat cryptococcosis

Cryptococcosis (Disease Associated with Pigeon Feces)

An opportunistic yeast infection strongly linked to bird droppings and immunocompromise.
Worldwide fungus, mostly in decaying matter
Yeast with an antigenic polysaccharide capsule
Isolated from fruits, milk, vegetation, soil, and pigeon feces
Common in AIDS/immunocompromised patients

Agent: Cryptococcus neoformans
Encapsulated yeast, round/ovoid, 4–6 µm diameter
In culture: whitish mucoid colonies within 2–3 days
Reservoir: pigeon droppings , nesting places, contaminated soil (nitrogenous soil, creatine favour growth)
Old buildings are a common source

Flucytosine and fluconazole — both used to treat cryptococcosis (Mycology Revision: Fungal Infections, Histoplasmosis & Cryptococcosis)
Discuss the causative agent, pathogenesis, clinical manifestation and treatment of Cryptococcosis (20 marks) (Cryptococcal Meningitis: Symptoms, Causes & Fungal Treatment)
Discuss the causative agent, clinical manifestation and treatment of Cryptococcosis (20 marks) *(if chosen)* (Medical Microbiology III Exam: Viruses, Fungi & Diagnosis)
Fungal cells reproduce by budding in candidiasis, cryptococcosis, and sporotrichosis (High-Yield Medical Mycology: Top CAT Exam Questions & Drugs)
Q: List four clinical manifestations of Cryptococcosis. (Medical Mycology Q&A Section A.. )
What to write if asked: Cryptococcosis — causative agent, pathogenesis, lab diagnosis, treatment (Cytomegalovirus (CMV) Guide: Pathogenesis, Dx & Treatment)