Polycystic Kidney Disease

Also written as PKD.

Berry aneurysms are associated with Autosomal Dominant Polycystic Kidney Disease (ADPKD).

What our notes say

Berry aneurysms are associated with Autosomal Dominant Polycystic Kidney Disease (ADPKD). (Comprehensive Heart Pathology Notes 🫀)
Premature neonate with suspected polycystic kidney disease (renal pathology — Past Paper Questions & Answers)
Her renal scan suggests a diagnosis of autosomal dominant polycystic kidney disease (ADPKD). (CNS PATHOLOGY — Past Paper Questions & Answers)
Causes: diabetes mellitus (leading cause), hypertension (second leading), chronic glomerulonephritis, polycystic kidney disease, recurrent obstruction/reflux nephropathy (Ovarian & Colorectal Cancer: Risks, Pathogenesis, Staging)
| Examples | Huntington disease, Marfan syndrome, familial hypercholesterolemia, achondroplasia, polycystic kidney disease | Cystic fibrosis, phenylketonuria, sickle cell anaemia, Tay-Sachs disease, galactosemia | (Genetic Disorders CAT: Key Terms & Inheritance Patterns Explained)
Disorders to know as a set: Marfan syndrome (fibrillin-1), Huntington disease (trinucleotide repeat), familial hypercholesterolemia (LDL receptor defect), polycystic kidney disease, hereditary spherocytosis (~75% of cases) (Clinical Genetics: Master Mendelian Disorders & Molecular Basis)