Medical Physiology Ii | MCQ Quiz | OmpathStudy Kenya

Practice 98 MCQs on Medical Physiology Ii with OmpathStudy. Built for Kenyan medical and health students to revise key concepts and prepare for exams.

Questions, Answers & Explanations

  1. Q1. Which of the following statements is FALSE?

    Answer: Longest intestinal transit time occurs in the ascending colon

  2. Q2. Which tissue layer provides for primary digestive motility?

    Answer: Muscularis mucosa

  3. Q3. Which statement about bile is true?

    Answer: Salts make cholesterol more water-soluble

  4. Q4. Which statement regarding the swallowing reflex is false?

    Answer: Has its reflex centers in the cervical segments of the spinal cord

  5. Q5. Which of the following statements is TRUE?

    Answer: Nitric oxide is the major neurotransmitter for gastrointestinal smooth muscle relaxation

  6. Q6. What is false about tonic contractions?

    Answer: Is caused by repeated spike waves

  7. Q7. Which of the following is characteristic of the segmenting movements in the small intestine?

    Answer: All of the above

  8. Q8. Secretion of saliva increases in all of the below except

    Answer: A subject thinks of unappetizing food

  9. Q9. Defecation is a reflex action

    Answer: That is coordinated by reflex centers in the sacral cord

  10. Q10. In the stomach

    Answer: Pepsinogen is converted to pepsin by hydrochloric acid

  11. Q11. Intestinal secretions contain

    Answer: Enzymes that hydrolyze disaccharides

  12. Q12. A 55-year-old man with chronic alcohol consumption presents with nonspecific complaints of dyspepsia. Examination reveals destruction of gastric glands. This predisposes him to

    Answer: Anemia

  13. Q13. Pancreatic secretions have many of the same ions as plasma, but concentrations differ. Which is true?

    Answer: Higher secretion rate increases bicarbonate and decreases chloride; plasma has less bicarbonate and more chloride

  14. Q14. A patient with trigeminal neurapraxia would have the greatest difficulty with

    Answer: Chewing

  15. Q15. Which statement is false about the normally innervated stomach?

    Answer: Cannot secrete HCl when H1 histamine receptors are blocked

  16. Q16. Passage of gastric contents to the duodenum may cause all except

    Answer: Contraction of the sphincter of Oddi

  17. Q17. Migrating motility complexes (MMCs) occur every 90 minutes between meals. Absence of MMCs increases

    Answer: Intestinal bacteria

  18. Q18. The cells of the liver

    Answer: Help maintain normal blood glucose

  19. Q19. Which statement is incorrect about free fatty acids in plasma?

    Answer: Decrease when blood adrenaline rises

  20. Q20. Trypsin inhibitor

    Answer: Inhibits trypsin activation in the pancreas

  21. Q21. Which statement is false about impaired intestinal absorption?

    Answer: Iodide deficiency reduces thyroid size

  22. Q22. The most abundant bile acid is

    Answer: Cholic acid

  23. Q23. The total circulating bile salt pool is approximately

    Answer: 3.5 g

  24. Q24. Fat stores in adults

    Answer: Release fatty acids with increased sympathetic activity

  25. Q25. The cause of jaundice is likely to be

    Answer: Hemolysis if urine is darker than normal

  26. Q26. Diminished liver function may result in an increase in all except

    Answer: Albumin-to-globulin ratio

  27. Q27. Which statement is incorrect about portal hypertension?

    Answer: Portal blood flow through the liver increases

  28. Q28. Which statement is false about obesity?

    Answer: Unlikely on a high-protein diet even with excess calories

  29. Q29. Which hormone is not a glycoprotein?

    Answer: TRH

  30. Q30. The three glycoprotein hormones (each with alpha and beta subunits) produced by the pituitary are

    Answer: TSH, LH, FSH

  31. Q31. Growth hormone secretion is increased by all except

    Answer: Pharmacologic hydrocortisone

  32. Q32. Which statement is true regarding oxytocin?

    Answer: All of the above

  33. Q33. Which inhibits lactation?

    Answer: Bromocriptine

  34. Q34. The major stimulator of parathyroid hormone release is

    Answer: Fall in plasma ionized calcium

  35. Q35. Which hormone lowers plasma ionized calcium?

    Answer: Calcitonin

  36. Q36. For a euthyroid woman (not pregnant/nursing, no meds), the recommended daily iodine intake is

    Answer: 150 μg

  37. Q37. Iodine is concentrated in thyroid follicular cells by

    Answer: Secondary active transport

  38. Q38. Which does not occur after adrenalectomy?

    Answer: Glucose intolerance

  39. Q39. Which is correct?

    Answer: Beta cells release equimolar insulin and C-peptide

  40. Q40. Hashimoto’s thyroiditis is best described as

    Answer: Autoimmune destruction due to anti-thyroglobulin antibodies

  41. Q41. The most common cause of hyperthyroidism is

    Answer: Graves’ disease

  42. Q42. Cushing’s syndrome refers to

    Answer: Disease from abnormally high cortisol

  43. Q43. "Cushing’s disease" specifically refers to

    Answer: Pituitary tumor

  44. Q44. A potent stimulator of insulin secretion is

    Answer: GLP-1

  45. Q45. Insulin-dependent glucose uptake in muscle/adipose tissue is mediated by

    Answer: GLUT4

  46. Q46. Glucagon (in high concentrations, e.g., type 1 diabetes) facilitates all except

    Answer: Muscle glycogenolysis

  47. Q47. The most sensitive test of pancreatic beta-cell insulin secretory reserve is

    Answer: Oral glucose tolerance test

  48. Q48. The major site of steroidogenesis is

    Answer: Smooth ER

  49. Q49. If glomerular capillary hydrostatic pressure = 40 mmHg, Bowman’s space pressure = 12 mmHg, colloid osmotic pressure = 25 mmHg, and no protein in ultrafiltrate, net filtration pressure is

    Answer: 8 mmHg

  50. Q50. Most reabsorbed water in the kidney occurs in the

    Answer: Proximal tubules

  51. Q51. Which is true about glucose reabsorption?

    Answer: Glucose enters epithelial cells via apical secondary active transport

  52. Q52. Furosemide’s undesirable side effect due to its site of action is

    Answer: Decreased urine-concentrating ability

  53. Q53. Micturition occurs due to

    Answer: Parasympathetic activation to bladder

  54. Q54. The main barrier preventing albumin passage across glomerular capillaries is

    Answer: Anionic proteins in basement membrane

  55. Q55. The mechanism generating medullary interstitial hypertonicity is

    Answer: Active NaCl transport in thick ascending limb

  56. Q56. The macula densa senses Na/Cl via

    Answer: NKCC2 transporter

  57. Q57. Ammonia is an effective urinary buffer because

    Answer: Tubules are impermeable to NH4⁺

  58. Q58. As plasma glucose rises above normal

    Answer: Reabsorption increases then plateaus

  59. Q59. In the nephron

    Answer: Collecting duct osmolality ↑ with vasopressin

  60. Q60. For actively reabsorbed substances, the maximal transport rate

    Answer: Is termed tubular transport maximum (Tm)

  61. Q61. Which statement is correct?

    Answer: Proximal tubule urea reabsorption > cortical collecting tubule

  62. Q62. The renal countercurrent mechanism depends on

    Answer: Loop of Henle and vasa recta

  63. Q63. Increased extracellular osmolality will

    Answer: Stimulate osmoreceptors and ADH secretion

  64. Q64. Why is milk produced only after delivery?

    Answer: High progesterone/estrogen suppress milk production

  65. Q65. The blood-testis barrier is formed by tight junctions between

    Answer: Sertoli cells

  66. Q66. Incorrect about the blood-testis barrier

    Answer: Leydig cells are part of it

  67. Q67. The major trophic hormone for Sertoli cells and aromatase stimulator is

    Answer: Melatonin

  68. Q68. Which cells undergo meiotic division?

    Answer: Primary spermatocytes

  69. Q69. Average number of spermatids from one spermatogonium

    Answer: 128

  70. Q70. Time for germ cell → mature sperm

    Answer: 74 days

  71. Q71. Sildenafil enhances erections by

    Answer: Inhibiting cGMP phosphodiesterase

  72. Q72. Sildenafil primarily inhibits

    Answer: cGMP-PDE5

  73. Q73. Which hormone peaks in mid-luteal phase?

    Answer: Inhibin B

  74. Q74. Without fertilization, endometrial shedding occurs because

    Answer: Corpus luteum involution ↓ estradiol/progesterone

  75. Q75. hCG is detectable in pregnancy as early as days post-fertilization

  76. Q76. hCG is similar to

    Answer: FSH

  77. Q77. hCG acts on

    Answer: LH receptor

  78. Q78. Normal lactation requires

    Answer: E + P + insulin + cortisol + prolactin

  79. Q79. Huntington’s hyperkinesia is due to neuron loss in

    Answer: Intrastriatal GABAergic/cholinergic system

  80. Q80. The cerebellum receives sensory input from

    Answer: All of the above

  81. Q81. Climbing fiber input to the cerebellum comes from

    Answer: Inferior olivary complex

  82. Q82. Basal ganglia neurotransmitters include all except

    Answer: Glycine

  83. Q83. Basal ganglia functions include all except

    Answer: Initiating reflex movements

  84. Q84. Basal ganglia send direct projections to

    Answer: VA/VL thalamic nuclei

  85. Q85. Parkinsonism manifestations include all except

    Answer: Kinetic tremors

  86. Q86. Cerebellar coordination involves all except

    Answer: Movement decomposition

  87. Q87. The limbic system’s role in emotional behavior includes all except

    Answer: Generalized sympathetic stimulation

  88. Q88. β-waves on EEG

    Answer: Occur during REM sleep

  89. Q89. The prefrontal area is concerned with all except

    Answer: Movement timing planning

  90. Q90. False about the primary motor area

    Answer: Face is unilaterally represented

  91. Q91. Primary motor cortex output goes to ; basal ganglia output goes to

    Answer: Corticospinal tract, extrapyramidal system

  92. Q92. Primary motor cortex lesions cause

    Answer: Loss of fine but not gross movements

  93. Q93. The nigrostriatal pathway’s main neurotransmitter is

    Answer: Dopamine

  94. Q94. Delta waves (0.5–4 Hz) occur in

    Answer: Stage 4 sleep

  95. Q95. The circadian rhythm generator (hypothalamus) receives input chiefly from

    Answer: Retina

  96. Q96. Memory consolidation (short-term → long-term) occurs in the

    Answer: Hippocampus

  97. Q97. The Papez circuit includes

    Answer: Hypothalamus

  98. Q98. False about the motor homunculus

    Answer: Located at postcentral gyrus

View on OmpathStudy