Medical Physiology Ii | MCQ Quiz | OmpathStudy Kenya

Practice 97 MCQs on Medical Physiology Ii with OmpathStudy. Built for Kenyan medical and health students to revise key concepts and prepare for exams.

Questions, Answers & Explanations

  1. Q1. Which of the following statements is FALSE?

    Answer: Longest intestinal transit time occurs in the ascending colon

  2. Q2. Which tissue layer provides for primary digestive motility?

    Answer: Muscularis mucosa

  3. Q3. Which statement about bile is true?

    Answer: Salts make cholesterol more water-soluble

  4. Q4. Which statement regarding the swallowing reflex is false?

    Answer: Has its reflex centers in the cervical segments of the spinal cord

  5. Q5. Which of the following statements is TRUE?

    Answer: Nitric oxide is the major neurotransmitter for gastrointestinal smooth muscle relaxation

  6. Q6. What is false about tonic contractions?

    Answer: Is caused by repeated spike waves

  7. Q7. Which of the following is characteristic of the segmenting movements in the small intestine?

    Answer: All of the above

  8. Q8. Secretion of saliva increases in all of the below except

    Answer: A subject thinks of unappetizing food

  9. Q9. Defecation is a reflex action

    Answer: That is coordinated by reflex centers in the sacral cord

  10. Q10. In the stomach

    Answer: Pepsinogen is converted to pepsin by hydrochloric acid

  11. Q11. Intestinal secretions contain

    Answer: Enzymes that hydrolyze disaccharides

  12. Q12. A 55-year-old man with chronic alcohol consumption presents with nonspecific complaints of dyspepsia. Examination reveals destruction of gastric glands. This predisposes him to

    Answer: Anemia

  13. Q13. A patient with trigeminal neurapraxia would have the greatest difficulty with

    Answer: Chewing

  14. Q14. Which statement is false about the normally innervated stomach?

    Answer: Cannot secrete HCl when H1 histamine receptors are blocked

  15. Q15. Passage of gastric contents to the duodenum may cause all except

    Answer: Contraction of the sphincter of Oddi

  16. Q16. Migrating motility complexes (MMCs) occur every 90 minutes between meals. Absence of MMCs increases

    Answer: Intestinal bacteria

  17. Q17. The cells of the liver

    Answer: Help maintain normal blood glucose

  18. Q18. Which statement is incorrect about free fatty acids in plasma?

    Answer: Decrease when blood adrenaline rises

  19. Q19. Trypsin inhibitor

    Answer: Inhibits trypsin activation in the pancreas

  20. Q20. Which statement is false about impaired intestinal absorption?

    Answer: Iodide deficiency reduces thyroid size

  21. Q21. The most abundant bile acid is

    Answer: Cholic acid

  22. Q22. The total circulating bile salt pool is approximately

    Answer: 3.5 g

  23. Q23. Fat stores in adults

    Answer: Release fatty acids with increased sympathetic activity

  24. Q24. The cause of jaundice is likely to be

    Answer: Hemolysis if urine is darker than normal

  25. Q25. Diminished liver function may result in an increase in all except

    Answer: Albumin-to-globulin ratio

  26. Q26. Which statement is incorrect about portal hypertension?

    Answer: Portal blood flow through the liver increases

  27. Q27. Which statement is false about obesity?

    Answer: Unlikely on a high-protein diet even with excess calories

  28. Q28. Which hormone is not a glycoprotein?

    Answer: TRH

  29. Q29. The three glycoprotein hormones (each with alpha and beta subunits) produced by the pituitary are

    Answer: TSH, LH, FSH

  30. Q30. Growth hormone secretion is increased by all except

    Answer: Pharmacologic hydrocortisone

  31. Q31. Which statement is true regarding oxytocin?

    Answer: All of the above

  32. Q32. Which inhibits lactation?

    Answer: Bromocriptine

  33. Q33. The major stimulator of parathyroid hormone release is

    Answer: Fall in plasma ionized calcium

  34. Q34. Which hormone lowers plasma ionized calcium?

    Answer: Calcitonin

  35. Q35. For a euthyroid woman (not pregnant/nursing, no meds), the recommended daily iodine intake is

    Answer: 150 μg

  36. Q36. Iodine is concentrated in thyroid follicular cells by

    Answer: Secondary active transport

  37. Q37. Which does not occur after adrenalectomy?

    Answer: Glucose intolerance

  38. Q38. Which is correct?

    Answer: Beta cells release equimolar insulin and C-peptide

  39. Q39. Hashimoto’s thyroiditis is best described as

    Answer: Autoimmune destruction due to anti-thyroglobulin antibodies

  40. Q40. The most common cause of hyperthyroidism is

    Answer: Graves’ disease

  41. Q41. Cushing’s syndrome refers to

    Answer: Disease from abnormally high cortisol

  42. Q42. "Cushing’s disease" specifically refers to

    Answer: Pituitary tumor

  43. Q43. A potent stimulator of insulin secretion is

    Answer: GLP-1

  44. Q44. Insulin-dependent glucose uptake in muscle/adipose tissue is mediated by

    Answer: GLUT4

  45. Q45. Glucagon (in high concentrations, e.g., type 1 diabetes) facilitates all except

    Answer: Muscle glycogenolysis

  46. Q46. The most sensitive test of pancreatic beta-cell insulin secretory reserve is

    Answer: Oral glucose tolerance test

  47. Q47. The major site of steroidogenesis is

    Answer: Smooth ER

  48. Q48. If glomerular capillary hydrostatic pressure = 40 mmHg, Bowman’s space pressure = 12 mmHg, colloid osmotic pressure = 25 mmHg, and no protein in ultrafiltrate, net filtration pressure is

    Answer: 8 mmHg

  49. Q49. Most reabsorbed water in the kidney occurs in the

    Answer: Proximal tubules

  50. Q50. Which is true about glucose reabsorption?

    Answer: Glucose enters epithelial cells via apical secondary active transport

  51. Q51. Furosemide’s undesirable side effect due to its site of action is

    Answer: Decreased urine-concentrating ability

  52. Q52. Micturition occurs due to

    Answer: Parasympathetic activation to bladder

  53. Q53. The main barrier preventing albumin passage across glomerular capillaries is

    Answer: Anionic proteins in basement membrane

  54. Q54. The mechanism generating medullary interstitial hypertonicity is

    Answer: Active NaCl transport in thick ascending limb

  55. Q55. The macula densa senses Na/Cl via

    Answer: NKCC2 transporter

  56. Q56. Ammonia is an effective urinary buffer because

    Answer: Tubules are impermeable to NH4⁺

  57. Q57. As plasma glucose rises above normal

    Answer: Reabsorption increases then plateaus

  58. Q58. In the nephron

    Answer: Collecting duct osmolality ↑ with vasopressin

  59. Q59. For actively reabsorbed substances, the maximal transport rate

    Answer: Is termed tubular transport maximum (Tm)

  60. Q60. Which statement is correct?

    Answer: Proximal tubule urea reabsorption > cortical collecting tubule

  61. Q61. The renal countercurrent mechanism depends on

    Answer: Loop of Henle and vasa recta

  62. Q62. Increased extracellular osmolality will

    Answer: Stimulate osmoreceptors and ADH secretion

  63. Q63. Why is milk produced only after delivery?

    Answer: High progesterone/estrogen suppress milk production

  64. Q64. The blood-testis barrier is formed by tight junctions between

    Answer: Sertoli cells

  65. Q65. Incorrect about the blood-testis barrier

    Answer: Leydig cells are part of it

  66. Q66. The major trophic hormone for Sertoli cells and aromatase stimulator is

    Answer: Melatonin

  67. Q67. Which cells undergo meiotic division?

    Answer: Primary spermatocytes

  68. Q68. Average number of spermatids from one spermatogonium

    Answer: 128

  69. Q69. Time for germ cell → mature sperm

    Answer: 74 days

  70. Q70. Sildenafil enhances erections by

    Answer: Inhibiting cGMP phosphodiesterase

  71. Q71. Sildenafil primarily inhibits

    Answer: cGMP-PDE5

  72. Q72. Which hormone peaks in mid-luteal phase?

    Answer: Inhibin B

  73. Q73. Without fertilization, endometrial shedding occurs because

    Answer: Corpus luteum involution ↓ estradiol/progesterone

  74. Q74. hCG is detectable in pregnancy as early as days post-fertilization

  75. Q75. hCG is similar to

    Answer: FSH

  76. Q76. hCG acts on

    Answer: LH receptor

  77. Q77. Normal lactation requires

    Answer: E + P + insulin + cortisol + prolactin

  78. Q78. Huntington’s hyperkinesia is due to neuron loss in

    Answer: Intrastriatal GABAergic/cholinergic system

  79. Q79. The cerebellum receives sensory input from

    Answer: All of the above

  80. Q80. Climbing fiber input to the cerebellum comes from

    Answer: Inferior olivary complex

  81. Q81. Basal ganglia neurotransmitters include all except

    Answer: Glycine

  82. Q82. Basal ganglia functions include all except

    Answer: Initiating reflex movements

  83. Q83. Basal ganglia send direct projections to

    Answer: VA/VL thalamic nuclei

  84. Q84. Parkinsonism manifestations include all except

    Answer: Kinetic tremors

  85. Q85. Cerebellar coordination involves all except

    Answer: Movement decomposition

  86. Q86. The limbic system’s role in emotional behavior includes all except

    Answer: Generalized sympathetic stimulation

  87. Q87. β-waves on EEG

    Answer: Occur during REM sleep

  88. Q88. The prefrontal area is concerned with all except

    Answer: Movement timing planning

  89. Q89. False about the primary motor area

    Answer: Face is unilaterally represented

  90. Q90. Primary motor cortex output goes to ; basal ganglia output goes to

    Answer: Corticospinal tract, extrapyramidal system

  91. Q91. Primary motor cortex lesions cause

    Answer: Loss of fine but not gross movements

  92. Q92. The nigrostriatal pathway’s main neurotransmitter is

    Answer: Dopamine

  93. Q93. Delta waves (0.5–4 Hz) occur in

    Answer: Stage 4 sleep

  94. Q94. The circadian rhythm generator (hypothalamus) receives input chiefly from

    Answer: Retina

  95. Q95. Memory consolidation (short-term → long-term) occurs in the

    Answer: Hippocampus

  96. Q96. The Papez circuit includes

    Answer: Hypothalamus

  97. Q97. False about the motor homunculus

    Answer: Located at postcentral gyrus

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