Endocrine and Metabolic Pathology MCQs

8 clinical MCQs in General Pathology. Which of the following is a characteristic feature of Graves' disease? —. Kenya, Africa and global revision.

Questions, Answers & Explanations

1. Q1. Which of the following is a characteristic feature of Graves' disease? ---

   • Hypothyroidism
   • Exophthalmos
   • Low serum T3 and T4
   • High serum TSH
   • Hashimoto's thyroiditis

   Answer: Hypothyroidism

2. Q2. Pheochromocytoma is a tumor derived from ---

   • Adrenal cortex
   • Chromaffin cells of the adrenal medulla
   • Thyroid follicular cells
   • Parathyroid chief cells
   • Pancreatic beta cells

   Answer: Adrenal cortex

3. Q3. Cushing's syndrome is most commonly caused by ---

   • Exogenous glucocorticoid administration
   • Pituitary adenoma (Cushing's diseas
   • Adrenal adenoma
   • Ectopic ACTH production
   • Adrenal hyperplasia

   Answer: Exogenous glucocorticoid administration

4. Q4. Which type of thyroid carcinoma is associated with amyloid stroma and calcitonin production? ---

   • Papillary carcinoma
   • Follicular carcinoma
   • Medullary carcinoma
   • Anaplastic carcinoma
   • Hürthle cell carcinoma

   Answer: Papillary carcinoma

5. Q5. Type 1 Diabetes Mellitus is characterized by ---

   • Insulin resistance
   • Absolute insulin deficiency due to beta-cell destruction
   • Obesity as a primary risk factor
   • Onset typically in older adults
   • Normal C-peptide levels

   Answer: Insulin resistance

6. Q6. Primary hyperparathyroidism is most frequently caused by ---

   • Parathyroid hyperplasia
   • Parathyroid carcinoma
   • Solitary parathyroid adenoma
   • Chronic renal failure
   • Vitamin D deficiency

   Answer: Parathyroid hyperplasia

7. Q7. Conn's syndrome is characterized by the overproduction of ---

   • Cortisol
   • Epinephrine
   • Aldosterone
   • Testosterone
   • Growth hormone

   Answer: Cortisol

8. Q8. Which of the following is a common clinical manifestation of Acromegaly?

   • Short stature
   • Enlargement of hands and feet
   • Hypotension
   • Hypoglycemia
   • Thinning of the skin

   Answer: Short stature