83 clinical MCQs in Physiology. Which substance will cause smooth muscle relaxation?. Kenya, Africa and global revision.
Q1. Which substance will cause smooth muscle relaxation?
Answer: Secretin
Explanation: Vasoactive Intestinal Peptide (VIP) is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q2. Which does not take part in the stimulation of GI glands?
Answer: External Stimulus
Explanation: External Stimulus is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q3. Which of the following is the site of secretion of intrinsic factor?
Answer: Ileum
Explanation: Gastric fundus is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q4. Which of the following changes occurs during defecation?
Answer: External anal sphincter is contracted
Explanation: Internal anal sphincter is relaxed is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q5. Which of the following produce testosterone?
Answer: Interstitial cells of Leydig
Explanation: Interstitial cells of Leydig is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q6. Which of the following does not occur on presentation of a bolus of solid food to the mouth?
Answer: Stimulation of taste buds
Explanation: Stimulation of defecation reflex is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q7. The salivary secretion:
Answer: Is stimulated by most GIT hormones, especially gastrin
Explanation: Is markedly increased by parasympathetic stimulation is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q8. Chronic gastritis is often associated with the following:
Answer: Microcytic anemia
Explanation: Pernicious anemia is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q9. Vitamin B12 absorption:
Answer: Depends on passive diffusion
Explanation: Depends on the presence of intrinsic factor is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q10. The cephalic phase of gastric secretion:
Answer: Occurs when food reaches the stomach
Explanation: Is controlled by the vagus nerves is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q11. Gastric HCl secretion:
Answer: Is a passive process that occurs in all parts of the stomach
Explanation: Plays a significant role in iron absorption is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q12. Distension of the stomach:
Answer: Is associated with a decrease in its peristaltic movement
Explanation: Decreases the tone of the lower esophageal sphincter is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q13. Fructose is absorbed from the small intestine by:
Answer: Simple diffusion
Explanation: Facilitated diffusion is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q14. Vitamin C is absorbed from the small intestine by:
Answer: Passive diffusion
Explanation: Na⁺-dependent secondary active transport is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q15. Peristaltic rush is characterized by the following except:
Answer: They are strong peristaltic contractions
Explanation: They occur normally is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q16. Small intestine motility is stimulated by the following except:
Answer: Gastrin
Explanation: Secretin is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q17. Small intestine motility is inhibited by the following except:
Answer: Somatostatin
Explanation: Insulin is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q18. Emptying at the ileocecal region is promoted by:
Answer: Distension of cecum
Explanation: Distension of stomach is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q19. Emptying at the ileocecal region is inhibited by:
Answer: Gastroileal reflex
Explanation: Colonoileal reflex is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q20. The first portion of the stomach that food enters is the:
Answer: Body
Explanation: Cardia is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q21. Cholecystokinin from the intestinal wall is stimulated by the presence of:
Answer: Acid in the stomach
Explanation: Fats and protein in the duodenum is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q22. Which of the following hormones stimulates the gallbladder to release bile?
Answer: Enterokinase
Explanation: Cholecystokinin is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q23. Which of the following hormones stimulates the release of insulin from the pancreatic islet cells?
Answer: Enterocrinin
Explanation: Gastric Inhibitory Peptide is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q24. During the defecation reflex, the:
Answer: Diaphragm is lowered
Explanation: None of the above is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q25. Inhibition of the myenteric plexus leads to the following:
Answer: Increased secretion of secretin from the duodenum
Explanation: Decreased gut motility is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q26. The secretion of gastrin ceases:
Answer: When the stomach is distended by a meal
Explanation: When the pH of the gastric content is decreased below 2 is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q27. Stimulation of the submucosal plexus results in an increase of the following?
Answer: Motility of the gut
Explanation: Secretion of the gut is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q28. Secretin:
Answer: Stimulates a pancreatic secretion rich in enzymes
Explanation: Is released as a result of contact of acid chyme with the duodenal mucosa is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q29. About the GIT hormones affecting gastric function:
Answer: CCK and secretin increase both gastric secretion and motility
Explanation: GIP and VIP inhibit gastric secretion is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q30. Cholecystokinin:
Answer: Is released from gastric mucosal cells
Explanation: Release is stimulated by protein hydrolysates in the lumen of the small intestine is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q31. The major factor that stimulates the release of secretin into the bloodstream is:
Answer: The parasympathetic stimuli
Explanation: An acid pH of the chyme entering the duodenum is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q32. Deficiency of adrenal cortex hormones results in:
Answer: Addison disease
Explanation: Addison disease is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q33. Which of the following hormones promotes the excretion of potassium ions and the reabsorption of sodium ions?
Answer: Aldosterone
Explanation: Aldosterone is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q34. Which of these is true of the endocrine system?
Answer: Secretes hormones that are transported to target cells by blood
Explanation: All of the above is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q35. Actions of Luteinizing hormone in the male include:
Answer: Stimulating mitosis in spermatogonia
Explanation: Initiating spermatogenesis by stimulating seminiferous tubule epithelial cells is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q36. For calcium metabolism, all of the following are required except:
Answer: Vitamin D
Explanation: Thyroxine is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q37. All of the following are stimuli for growth hormone release except:
Answer: Hypoglycemia
Explanation: Obesity is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q38. The endocrine gland responsible for the body's circadian rhythm is the:
Answer: Thymus gland
Explanation: Pineal gland is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q39. A hormone involved in programming circadian rhythms:
Answer: Enkephalin
Explanation: Melatonin is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q40. Vitamin B12 is absorbed via:
Answer: Simple diffusion
Explanation: Endocytosis is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q41. Which is true regarding the adrenal hormones?
Answer: Cortisol is produced in response to elevated blood glucose
Explanation: Adrenaline is produced in the adrenal medulla is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q42. Regarding thyroid hormones:
Answer: T3 is converted to T4 by deiodinase
Explanation: T4 is converted to T3 by deiodinase is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q43. Which is true regarding cortisol?
Answer: Its production results in lowering of blood glucose
Explanation: Its level is highest just before sunrise is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q44. Which is true regarding autocrine communication?
Answer: Signals transmitted via the bloodstream
Explanation: Signals sent to the same cell that produced it or neighboring cells of the same type is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q45. Which is not true regarding insulin?
Answer: It is a peptide hormone
Explanation: Its secretion is stimulated by somatostatin is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q46. Which is true regarding growth hormone?
Answer: Maximal secretion occurs during the day
Explanation: Is secreted by the anterior pituitary is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q47. What is responsible for growth of internal organs after birth?
Answer: IGF-1
Explanation: IGF-1 is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q48. Autocrine communication refers to:
Answer: Signals transmitted via the bloodstream
Explanation: Signals sent to the same cell that produced it or neighboring cells of the same type is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q49. Which is true regarding hormone transporters?
Answer: Dopamine is transported by them
Explanation: They prolong the half-life of circulating hormones is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q50. Target cells are able to respond to specific hormones because:
Answer: They recognize the hormone-binding protein
Explanation: They have receptors that are specific to the hormone is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q51. Regarding GIT smooth muscle, constriction of the outermost layer of GIT smooth muscle results in:
Answer: Change in tube diameter
Explanation: Change in tube diameter is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q52. Food transit time is shortest through the:
Answer: Duodenum
Explanation: Esophagus is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q53. The stomach can accommodate approximately what volume of food?
Answer: 5 liters
Explanation: 2 liters is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q54. The protective mucus layer in the stomach is produced by:
Answer: Parietal cells
Explanation: Mucus cells is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q55. Inactive pepsinogen is converted to active pepsin in the stomach by:
Answer: Trypsin
Explanation: Gastric acid is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q56. Synthesis of gastric acid begins with the action of:
Answer: H⁺-K⁺ ATPase
Explanation: H⁺-K⁺ ATPase is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q57. Insulin secretion following arrival of carbohydrates is mediated by:
Answer: Gastrin
Explanation: Glucagon-like peptide 1 is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q58. Delayed stomach emptying may cause all except:
Answer: Nausea
Explanation: Diarrhea is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q59. When osmotically active molecules (e.g., lactose) exist in the colon:
Answer: Constipation is a common result
Explanation: The lumen contents are hypertonic is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q60. Which is not true regarding the MMC (Migrating Motor Complex)?
Answer: Normally originates in the stomach
Explanation: Has the same frequency as peristalsis is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q61. Which of these is not a characteristic of action potentials?
Answer: They are produced by voltage-regulated gates.
Explanation: Na⁺ and K⁺ gates open at the same time. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q62. Postsynaptic inhibition is produced by:
Answer: depolarization of the postsynaptic membrane.
Explanation: hyperpolarization of the postsynaptic membrane. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q63. Hyperpolarization of the postsynaptic membrane in response to glycine or GABA is produced by the opening of:
Answer: Sodium channels.
Explanation: Chloride channels. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q64. Nociceptors:
Answer: are absent in visceral organs.
Explanation: are activated by strong pressure, severe cold, heat, and chemicals. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q65. A generator potential:
Answer: always leads to an action potential.
Explanation: increases in amplitude with stimulus intensity. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q66. Sensory systems code for:
Answer: threshold, receptive field, adaptation, discrimination.
Explanation: modality, location, intensity, duration. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q67. Which of the following are correctly paired?
Answer: Neuropathic pain – withdrawal reflex.
Explanation: Second pain – C fibers. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q68. Which statement about the medulla oblongata is false?
Answer: Contains nuclei for cranial nerves.
Explanation: Contains the apneustic center. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q69. The reticular activating system:
Answer: is part of the reticular formation.
Explanation: All of the above. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q70. In emotion/motivation, the limbic system works with:
Answer: the thalamus.
Explanation: the hypothalamus. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q71. Verbal ability predominates in:
Answer: the left hemisphere of right-handed people.
Explanation: both A and B. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q72. Consolidation of short-term to long-term memory involves:
Answer: the substantia nigra.
Explanation: the hippocampus. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q73. Which autonomic receptor is blocked by hexamethonium at ganglia but not at the neuromuscular junction?
Answer: Adrenergic α receptors.
Explanation: Cholinergic nicotinic receptors. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q74. Which response is mediated by parasympathetic muscarinic receptors?
Answer: Bronchodilation.
Explanation: Erection. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q75. Which is a property of C fibers?
Answer: Slowest conduction velocity.
Explanation: Slowest conduction velocity. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q76. Compared to cones, rods:
Answer: adapt to darkness first.
Explanation: are more sensitive to low light. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q77. The basilar membrane of the organ of Corti:
Answer: The base is wider than the apex.
Explanation: The apex responds better to low frequencies. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q78. A feature of the sympathetic (not parasympathetic) nervous system:
Answer: Ganglia in effector organs.
Explanation: Preganglionic neurons originate in thoracolumbar spinal cord. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q79. Which autonomic receptor increases heart rate?
Answer: Adrenergic α.
Explanation: Adrenergic β₁. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q80. Cutting which structure causes left-eye blindness?
Answer: Optic nerve.
Explanation: Optic nerve. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q81. Which reflex causes monosynaptic excitation of ipsilateral homonymous muscle?
Answer: Stretch reflex.
Explanation: Stretch reflex. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q82. Which GI substance causes smooth muscle relaxation?
Answer: Secretin.
Explanation: VIP. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---
Q83. Site of intrinsic factor secretion:
Answer: Gastric antrum.
Explanation: Gastric fundus. is the physiologically correct answer per standard MBChB-level teaching on this topic. ---