Treatment of Infectious Disease: 5-case clinical quiz

MKU infectious disease treatment quiz: epiglottitis, tetanus, skin abscess in pregnancy, ascending cholangitis and chancroid, five case-based MCQs with answers.

Mount Kenya University · School of Medicine · Internal Medicine

Paper details

  • Paper: "WM Quiz: Treatment of Infectious Disease", five case-based multiple choice questions. The scan has no printed date or unit code, so it is filed as undated.
  • Question 1 has a lateral neck X-ray in the original. It is not reproduced here. The film shows a swollen epiglottis, and the question text gives everything needed to answer.
  • Answers: written by OmpathStudy for revision. They are not the official MKU marking scheme.
  • Topics tested: epiglottitis, tetanus, skin abscess in pregnancy, ascending cholangitis, genital ulcer disease.

1. Gilbert, 24, has a 3-day progressive sore throat, cannot swallow, drools, and has a muffled voice. He is distressed, febrile, HR 113, BP 94/55, WBC 21.7 with 88% polymorphs. A lateral neck film is shown (arrow). Diagnosis and action?

  • A. Viral laryngitis: supportive care, paracetamol, oral fluids
  • B. "Croup" caused by parainfluenza virus: admit for monitoring and supportive care
  • C. Epiglottitis caused by H. influenzae: examine the airway with surgical assistance given the risk of urgent tracheostomy
  • D. Group A streptococcal pharyngitis: amoxicillin for 10 days to prevent rheumatic fever

2. Nelson, 54, with alcoholism and diabetes, has an infected non-healing foot ulcer. He develops sudden neck pain and stiffness with no fever or headache. Temp 36.8, HR 134, BP 188/67, bilateral trismus, a stiff neck with spastic contraction, clear chest, and a foul-smelling wound. What is happening?

  • A. Bacterial meningitis: stat ceftriaxone and lumbar puncture
  • B. Tuberculous meningitis: RHZE, prednisolone and lumbar puncture
  • C. Cervical spine injury after alcohol binge: plain films
  • D. Botulism: supportive care
  • E. Tetanus: consult surgery for wound debridement, give tetanus immunoglobulin and immunisation, and diazepam for spasms

3. Gladys, 24, 12 weeks pregnant, has a 2-week painful boil on her right thigh, with subjective fever and malaise. She has normal vitals, a 3 cm indurated fluctuant abscess with no cellulitis, HIV negative, WBC 7.7. You incise and drain it (grossly purulent) and send a culture. What should you give her before discharge?

  • A. Amoxicillin-clavulanic acid for 7 days
  • B. Ciprofloxacin plus doxycycline to cover resistant Staph. aureus for 10 days
  • C. Symptomatic therapy with paracetamol and warm compresses
  • D. Co-trimoxazole (Septrin) 1920 mg daily for 5 days

4. Elizabeth, 49, has 2 weeks of abdominal pain, now with jaundice and fever. Temp 38.4, HR 124, BP 89/56, scleral icterus, right upper quadrant pain and a positive Murphy's sign, no peritonism. WBC 25.5, Hb 8.8, platelets 795,000, HIV negative. (Hint: severe sepsis: start with volume resuscitation and broad-spectrum antibiotics.) Then?

  • A. Cholecystitis: consult surgery for cholecystectomy
  • B. Viral hepatitis: check hepatitis B surface antigen and hepatitis C antibody
  • C. Perforated viscus: upright abdominal film and laparotomy
  • D. Ascending cholangitis: consult endoscopy for ERCP

5. Charles, 34, with HIV/AIDS, has a painful rounded 1 cm penile ulcer with heaped-up edges and tender suppurative inguinal lymphadenopathy. He is non-toxic. Cause and treatment?

  • A. Primary syphilis: darkfield microscopy and penicillin
  • B. Chancroid: azithromycin 1 g as a single dose
  • C. Lymphogranuloma venereum: doxycycline 100 mg twice daily for 21 days
  • D. Genital herpes: acyclovir 400 mg three times daily
  • E. Behçet's syndrome: high-dose corticosteroids

Model answers are on the page for subscribers.

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Compiled by Abongo Davis · Ompath Study · shared for MBChB students at Mount Kenya University and other universities.