Atypical Ductal Hyperplasia

Also written as ADH.

Moderately increased risk (about 4 to 5 times; atypical hyperplasia): atypical ductal hyperplasia and atypical lobular hyperplasia.

What our notes say

• Moderately increased risk (about 4 to 5 times; atypical hyperplasia): atypical ductal hyperplasia and atypical lobular hyperplasia. (General Surgery CAT 2 (MBSG 4600): 4 October 2021)
• Progression model: normal epithelium → atypical ductal hyperplasia → DCIS (confined by intact basement membrane) → invasive ductal carcinoma (Female & Male Genital Pathology: Ulcers, HPV, Endometriosis, Pre-eclampsia)
• Atypical Ductal Hyperplasia (ADH) — resembles DCIS but only partially fills duct (Exam Prep: Skin Infections, Psoriasis & Pemphigus)
• BRCA2 mutations → 1q gain, 16q loss → Flat epithelial atypia → Atypical ductal hyperplasia → DCIS → Invasive luminal carcinoma (Breast Cancer Guide: Epidemiology, Risk Factors & Classification)
• Atypical ductal hyperplasia (ADH): Partial involvement of ducts by cells resembling DCIS. (Disorders of the Vagina and Breast)

Related topics

• No Special Type
• Atypical Lobular Hyperplasia
• Triple Negative
• Invasive Carcinoma
• Duct Ectasia
• Fibroadenoma
• Breast Carcinoma
• Progesterone Receptor
• Acute Mastitis
• Breast Cancer