Bleeding Disorders
An X-linked recessive bleeding disorder caused by deficiency of clotting factor VIII, which affects males and is passed on by carrier mothers.
What our notes say
- An X-linked recessive bleeding disorder caused by deficiency of clotting factor VIII, which affects males and is passed on by carrier mothers. (Junior Clerkship in Internal Medicine (MBIM4100) main exam, Paper One: 31 Januar)
- Von Willebrand disease is the most common inherited bleeding disorder in the general population. (Haemostasis & Coagulation: Platelet Function & Bleeding Disorders)
- Foreign bodies, TB cavities, lupus (diffuse alveolar haemorrhage) and bleeding disorders can all cause pulmonary bleeding. (Paediatrics end of 2nd semester exam (MBPE 4300): 5 October 2021, 50 MCQs)
- Topics tested: anaemias, iron studies, haemolysis, bleeding disorders, haemochromatosis, acute kidney injury, glomerular and tubulointerstitial disease, kidney stones, dialysis and chronic kidney disease staging. (Internal Medicine End of Semester CAT (MBChB 4): haematology and renal, 30 MCQs )
- Topics tested: lupus and scleroderma, anaemias and bleeding disorders, lung and pleural disease, DVT and heart failure, HIV and antiretroviral therapy, gastroenterology, thyroid disease, gout, leukaemia and lymphoma, kidney disease and stroke. (Internal Medicine (MBIM 4100) special/supplementary exam, Paper Two: 14 August 2)
- Iron supplements for anaemia, and treatment of any underlying disorder (thyroid disease, bleeding disorder). (Year 6 Gynaecology CAT 1 (MBOG 6511): 13 December 2019, 4 short answers and 16 M)
Study material on Bleeding Disorders
- Haemostasis & Coagulation: Platelet Function & Bleeding Disorders
- Hematologic Malignancies and Bleeding Disorders
- Platelet Disorders
Practice questions on Bleeding Disorders
Most common inherited bleeding disorder?
- Hemophilia A
- Hemophilia B
- Von Willebrand disease
- Factor V Leiden
Answer: C. vWD affects ~1% of the population — the most common inherited bleeding disorder worldwide. ---
The most common inherited bleeding disorder is ---
- Hemophilia A
- Hemophilia B
- Von Willebrand disease Most common inherited bleeding disorder overall (~1% of population).
- Factor V Leiden
- Protein C deficiency Answer:
Answer: A.