Block Protein Synthesis
Also written as PKR.
Phosphorylates eIF2-alpha → blocks protein synthesis in the cell
What our notes say
- Phosphorylates eIF2-alpha → blocks protein synthesis in the cell (EXAM: Influenza, Viral Receptors & Spikes, Interferons, and Viral Pathogenesis)
- Tetracycline blocks protein synthesis by:A) Inhibiting binding of aminoacyl tRNA to ribosome (Molecular Biology,Molecular Genetics & Microbial-Biochemistry MCQs)
- Activate RNase L and PKR → degrade viral RNA, block protein synthesis. (Principles of Medical Microbiology and Parasitology LAQs & SAQs)