Degrade Extracellular Matrix
Also written as ECM.
Amoebapores (pore-forming proteins) and cysteine proteases kill host cells, degrade extracellular matrix and kill neutrophils, so there is little inflammation.
What our notes say
- Amoebapores (pore-forming proteins) and cysteine proteases kill host cells, degrade extracellular matrix and kill neutrophils, so there is little inflammation. (Amoebiasis: Entamoeba histolytica and the free-living amoebae)
- Local invasion — MMPs (matrix metalloproteinases) degrade extracellular matrix. (Cancer Pharmacology: Cell Cycle, Oncogenes & Drug Targets)
- Invasion and Cytolysis:Trophozoites invade the intestinal mucosa, particularly the crypts of Lieberkühn, using:Cysteine proteases: Degrade extracellular matrix (ECM) and inactivate complement factor C3. (Amebae)