Filariasis

Culex species are major vectors of filariasis nematodes

What our notes say

Culex species are major vectors of filariasis nematodes (Medical Entomology Past Paper MCQs)
Vector: Wuchereria bancrofti (filariasis), Rift Valley fever, West Nile virus — transovarial transmission (adults emerge already infected) (YEAR 3 PARASITOLOGY NOTES)
Lymphatic obstruction: filariasis, post-mastectomy lymphoedema (or tumour infiltration of lymphatics). (Eoy paper 2 gen systemic Patho 2025 — Past Paper Questions & Answers)
Lymphatic obstruction (lymphoedema) — e.g. filariasis, and post-surgical/post-radiotherapy lymph node dissection (e.g. after axillary clearance in breast cancer) or tumour infiltration of lymphatics. (General & Systemic Pathology SAQ Paper II — 15 July 2025 (MBPA 3500, MKU Year 3,)
Lymphatic obstruction → impaired drainage; e.g. filariasis, post-mastectomy lymphoedema (General & Systemic Pathology SAQ — Paper II)
| Diethylcarbamazine (DEC) | Immobilises microfilariae + enhances immune recognition | Lymphatic filariasis (Wuchereria bancrofti, Brugia) · loiasis · tropical eosinophilia | Mazzotti-like reaction · contraindicated in onchocerciasis (can cause ocular damage) | (Pharmco Notes)