Immune Thrombocytopenia

Also written as ITP.

| Increased destruction | Immune thrombocytopenia (ITP), drug‑induced (e.g., quinine, penicillins), disseminated intravascular coagulation (sepsis, severe malaria), hypersplenism (schistosomiasis, portal hypertension) |

What our notes say

• | Increased destruction | Immune thrombocytopenia (ITP), drug‑induced (e.g., quinine, penicillins), disseminated intravascular coagulation (sepsis, severe malaria), hypersplenism (schistosomiasis, portal hypertension) | (Thrombocytopenia and platelet disorders)
• Immune thrombocytopenia → auto‑antibodies bind platelet GPIIb/IIIa → Fc‑mediated splenic phagocytosis → thrombocytopenia. (Thrombocytopenia and platelet disorders)
• Neutropenia and thrombocytopenia — from direct marrow effects and immune-mediated destruction (HIV-associated immune thrombocytopenia resembles ITP) (Hematology & Blood Transfusion Pathology: MDS, Stem Cell Transplant)
• Also used in: immune thrombocytopenia, post-transfusion purpura, alloimmune neonatal thrombocytopenia ( Transfusion: Governance, Donor Selection & Blood Groups)
• | Drug most commonly causing immune thrombocytopenia | Heparin · quinine · quinidine | (Platelet Disorders)

Study material on Immune Thrombocytopenia

• Thrombocytopenia and platelet disorders
• Platelet Disorders

Related topics

• Platelet Function
• Immune Thrombocytopenic Purpura
• Von Willebrand Disease
• Leukocyte Alkaline Phosphatase
• Aldrich Syndrome
• Thrombotic Thrombocytopenic Purpura
• Aplastic Anemia
• Direct Antiglobulin Test
• Disseminated Intravascular Coagulation
• Intravascular Coagulation