Thrombotic Thrombocytopenic Purpura
Also written as TTP.
A provisional diagnosis of Thrombotic Thrombocytopenic Purpura (TTP) is made and the patient is referred for plasma exchange following placement of central line.
What our notes say
- A provisional diagnosis of Thrombotic Thrombocytopenic Purpura (TTP) is made and the patient is referred for plasma exchange following placement of central line. (Haematology paper 1 Past Papers — Past Paper Questions & Answers)
- A provisional diagnosis of Thrombotic Thrombocytopenic Purpura (TTP) is made and the patient is referred for plasma exchange following placement of a central line. (Hematopathology MCQs & Essays: MBChB Exam Revision Guide)
- Thrombotic Thrombocytopenic Purpura (TTP) is characterized by a deficiency of ADAMTS13, leading to the accumulation of ultra-large VWF multimers, causing microangiopathic hemolytic anemia, severe thrombocytopenia, and neurological/renal dysfunction. (Platelet Disorders)
- In which two conditions are platelet transfusions generally contraindicated due to the risk of worsening thrombosis? → Thrombotic Thrombocytopenic Purpura (TTP) and Hemolytic Uremic Syndrome (HUS). (Platelet Disorders)
- Thrombotic thrombocytopenic purpura (TTP) — ADAMTS13 deficiency causing microthrombi and MAHA (Haematopathology MCQs: Blood Disorders & Anemia Explained)
- Uses: replacement of coagulation factors when specific concentrates unavailable; massive transfusion; liver disease; DIC; after cardiopulmonary bypass; reverse warfarin; thrombotic thrombocytopenic purpura ( Transfusion: Governance, Donor Selection & Blood Groups)
Study material on Thrombotic Thrombocytopenic Purpura
- Platelet Disorders
- Hematopathology MCQs & Essays: MBChB Exam Revision Guide
- hematopathology
- Renal Vascular Diseases: Nephrosclerosis & Renal Artery Stenosis
- Hematology MCQs
- Here are all 45 questions, complete with full stems, choices, and answers.
- Renal, Liver, Cardiac & Adrenal Function Tests for Year 3
- Haematopathology MCQs: Blood Disorders & Anemia Explained