Interstitial Lung Diseases
Also written as ILD.
Interstitial lung diseases (ILD), or diffuse parenchymal lung diseases, are a heterogeneous group of more than 200 disorders that cause inflammation and/or fibrosis of the lung interstitium (alveolar walls and the tissue around airways and vessels).
What our notes say
- Interstitial lung diseases (ILD), or diffuse parenchymal lung diseases, are a heterogeneous group of more than 200 disorders that cause inflammation and/or fibrosis of the lung interstitium (alveolar walls and the tissue around airways and vessels). (Interstitial Lung Diseases)
- Idiopathic Pulmonary Fibrosis (IPF): A chronic, progressive interstitial lung disease of unknown etiology characterized by Usual Interstitial Pneumonia (UIP) pattern. (Lung Pathology — Must-Know)
- What are the two smoking-related interstitial lung diseases discussed, and what is a shared histological feature? → Desquamative Interstitial Pneumonia (DIP) and Respiratory Bronchiolitis (RB-ILD). (Respiratory Pathology 1b)
- Interstitial Lung Diseases — Year 4 Internal Medicine (Respiratory) Notes (Interstitial Lung Diseases)
- | Osimertinib | EGFR tyrosine kinase inhibitor | EGFR-mutant adenocarcinoma | Rash, diarrhoea, interstitial lung disease | (Lung Cancer)
- Causes of interstitial lung disease in infants include all EXCEPT: (Paediatrics end of 2nd semester exam (MBPE 4300): 5 October 2021, 50 MCQs)
Study material on Interstitial Lung Diseases
- Interstitial Lung Diseases
- Respiratory Pathology 1b
- Lung Pathology — Must-Know
- Respiratory System Pathology 1A
- Paediatrics end of 2nd semester exam (MBPE 4300): 5 October 2021, 50 MCQs
- Internal Medicine Respiratory CAT 1: 30 MCQs and 5 short answer questions
- Respiratory Pathology 1b
- Respiratory Pathology 1b
- Respiratory Pathology 2
Practice questions on Interstitial Lung Diseases
A patient with systemic sclerosis develops bilateral interstitial lung disease. The most common histologic pattern in systemic sclerosis lung involvement is
- UIP pattern identical to IPF
- Cryptogenic organizing pneumonia pattern
- NSIP (nonspecific interstitial pneumonia) pattern
- Desquamative interstitial pneumonia pattern
Answer: C. NSIP is the most common histologic pattern of lung involvement in collagen vascular diseases, particularly systemic sclerosis. UIP pattern can also occur but NSIP predominates. ---
A patient with rheumatoid arthritis develops progressive bilateral interstitial lung disease. Biopsy shows diffuse uniform interstitial fibrosis without temporal heterogeneity and no honeycombing. The pattern is
- UIP pattern identical to IPF
- NSIP (nonspecific interstitial pneumonia) pattern
- Cryptogenic organizing pneumonia pattern
- Desquamative interstitial pneumonia pattern
Answer: B. NSIP is the most common pattern in collagen vascular disease lung involvement. It lacks the temporal heterogeneity of UIP and typically has no honeycombing or fibroblastic foci. Prognosis is better than IPF. ---