Ketone Bodies

Ketone bodies are organic acids that accumulate in blood, causing metabolic acidosis with high anion gap

What our notes say

• Ketone bodies are organic acids that accumulate in blood, causing metabolic acidosis with high anion gap (Chemical Pathology Practice Examination)
• NADPH can be converted into acetyl-coA which can undergo the TCA cycle or proceed to form ketone bodies for energy. (Medical Physiology Assorted SAQs — With Answers (Past Paper Study Guide))
• This produces excessive ketone bodies (acetoacetate, beta-hydroxybutyrate, and acetone) (Chemical Pathology Practice Examination)
• Ketone bodies: Acetoacetate, β-hydroxybutyrate, acetone (Medical Physiology Section A - Complete Questions and Comprehensive Answers)
• Increases ketogenesis: In periods of fasting, glucagon stimulates the liver to convert fatty acids to ketone bodies. (Medical Physiology Pp2 Year 2)
• Ketogenesis: The liver produces ketone bodies from fatty acids, which become a primary energy source during prolonged fasting. (Integrated Tissue Metabolism -LAQs and SAQs)

Study material on Ketone Bodies

• Integrated Tissue Metabolism -LAQs and SAQs

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