Metacarpals
It is the joint between the first metacarpal and the trapezium (angle formed with the first phalanx is relevant to thumb movements)
What our notes say
- It is the joint between the first metacarpal and the trapezium (angle formed with the first phalanx is relevant to thumb movements) (Aponeurosis — Anatomy Question Bank)
- It is often associated with Albright hereditary osteodystrophy, which includes short stature, round face, short metacarpals/metatarsals, and subcutaneous calcifications. (ENDOCRINE PATHOLOGY)
- An X ray revealed a well circumscribed oval lucency in the 2nd metacarpal bone surrounded by a thin rim of radiodense bone. (pathology essays — Past Paper Questions & Answers)
- Compare: the deep palmar arch (mainly radial artery) lies deeper, gives palmar metacarpal arteries (Aponeurosis — Anatomy Question Bank)
- Deep palmar arch (mainly radial) → palmar metacarpal arteries (Master First-Year Anatomy: Must-Know Essays & Key Concepts)
- Albright's hereditary osteodystrophy: short stature, short 4th metacarpal, obesity, round face, intellectual disability. (Endocrine & Renal Pathology)
Study material on Metacarpals
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Practice questions on Metacarpals
An infant born at term is examined, and there is abnormal fusion of the 3rd, 4th, and 5th digits of the left hand. A radiograph of the left hand shows transformation of metacarpals I, II, III, and V to short, carpal-like bones. A mutation involving which of the following genes most likely led to these findings?
- CFTR
- FGFR3
- HOXD13
- SHH
- TBX5
Answer: C. This gene is in the homeobox family of genes producing transcription factors that control morphogenesis, including limb development. Mutations may lead to lack of separation (syndactyly). ---