Rickets
The following are radiographic features of rickets EXCEPT:
What our notes say
- The following are radiographic features of rickets EXCEPT: (Paediatrics Year 4 MBChB end of semester CAT: triage, newborn care, growth and d)
- Renal osteodystrophy: rickets, bone pain and deformity (low vitamin D, high phosphate and PTH) (Paediatrics and Child Health end of semester examination (MBPE): 10 January 2023)
- Topics tested: dehydration and shock, neonatal sepsis, pathological jaundice, malnutrition, tetralogy of Fallot, milestones, Down syndrome, meningitis, birth asphyxia, prematurity, breast milk and rickets. (Paediatrics Year 4 MBChB end of semester CAT: triage, newborn care, growth and d)
- Topics tested: rickets, kwashiorkor and marasmus, milestones and growth, breastfeeding, tuberculosis, asthma, croup, epiglottitis, neonatal jaundice, biliary atresia, neonatal sepsis, resuscitation and prematurity. (Paediatrics end of first trimester exam (MBPE 4300): 27 November 2018, 49 of 50 )
- Radiological signs of rickets include all the following EXCEPT: (Paediatrics end of first trimester exam (MBPE 4300): 27 November 2018, 49 of 50 )
- Risk factors for developing rickets include all the following EXCEPT: (Paediatrics main exam (MBPE 4300): 24 January 2022, Paper One, 100 MCQs, 2 short)
Study material on Rickets
- Paediatrics main exam (MBPE 4300): 24 January 2022, Paper One, 100 MCQs, 2 short essays and 2 long essays
- Paediatrics end of first trimester exam (MBPE 4300): 27 November 2018, 49 of 50 MCQs
- Paediatrics end of fourth year main exam: 1 July 2019, Paper One, 99 of 100 MCQs and essays
- Paediatrics Year 4 MBChB end of semester CAT: triage, newborn care, growth and development, 30 MCQs and 5 short answers
- Paediatrics end of fourth year special supplementary exam: August 2019, Paper One, 87 of 100 MCQs
- Complete Nutrition Science: Macronutrients & Health Foundations
- GENETIC DISORDERS SAQs EXAMINATION
Practice questions on Rickets
: Vitamin D-resistant rickets represents which unusual inheritance pattern?
- Autosomal recessive
- Mitochondrial
- X-linked dominant
- Y-linked
- Usually mediated by non-specific mechanisms
Answer: C. Vitamin D-resistant rickets is one of the few X-linked dominant conditions, making it an exception to the rule that almost all X-linked disorders are recessive. ---
Osteomalacia in adults (rickets in children) is caused by
- Excess vitamin D causing hypercalcemia and soft bones
- Fluoride toxicity causing dense brittle bones
- Vitamin D deficiency or phosphate wasting → defective bone mineralization → soft bones
- Excess PTH causing bone resorption
Answer: C. Osteomalacia: inadequate mineralization of osteoid (bone matrix laid down but not calcified). Causes: vitamin D deficiency (most common), malabsorption, renal disease (impaired 1-alpha hydroxylation), phenytoin (accelerates vitamin D catabolism), X-linked hypophosphatemia (FGF23 excess). Features: bone pain, muscle weakness, waddling gait, Looser's zones (pseudofractures) on X-ray. Biochem: low Ca, low PO4, high ALP,