Stromal Tumors
Sex cord-stromal tumors (Sertoli/Leydig) are uncommon and usually benign
STROMAL TUMORS
- Breast stroma = intralobular (gives biphasic tumors) vs interlobular (gives connective-tissue tumors as elsewhere in the body)
- Fibroadenoma & phyllodes tumor are both driven by MED12 mutations
Read this in Exam Prep: Skin Infections, Psoriasis & Pemphigus
What our notes say
- Sex cord-stromal tumors (Sertoli/Leydig) are uncommon and usually benign (MALE REPRODUCTIVE SYSTEM PATHOLOGY)
- Sex cord-stromal tumors, including granulosa cell tumor, Sertoli-Leydig cell tumor, fibroma, and thecoma. (Pathology Practical Revision Guide)
- Discuss the etiopathogenesis and morphology of sex cord stromal tumors. (pathology essays — Past Paper Questions & Answers)
- Intro: This section covers benign and malignant breast disease — benign epithelial lesions (and their cancer-risk stratification), inflammatory/infective breast disorders, stromal tumors, and breast carcinoma (the most clinically important topic — focus heavily here for exams). (Exam Prep: Skin Infections, Psoriasis & Pemphigus)
- Sex cord-stromal tumors (Sertoli/Leydig) = uncommon, usually benign (Quick Guide: Male Reproductive System Pathology, Testis, Penis)