Systemic Fungal Infections
More precisely, both are used to treat systemic fungal infections including cryptococcal meningitis, and both can penetrate the CNS.
What our notes say
- More precisely, both are used to treat systemic fungal infections including cryptococcal meningitis, and both can penetrate the CNS. (Medical Mycology Q&A Section A.. )
- All other options are true systemic fungal infections treatable with Amphotericin B. (📚 MEDICAL VIROLOGY & MYCOLOGY — MCQ BANK)
Study material on Systemic Fungal Infections
Practice questions on Systemic Fungal Infections
Amphotericin B, a polyene antifungal, would typically be used to treat all of the following severe systemic fungal infections EXCEPT:
- Tinea unguium
- Systemic candidiasis
- Cryptococcal meningitis
- Disseminated histoplasmosis
Answer: A. Amphotericin B is a potent broad-spectrum antifungal reserved for severe, life-threatening systemic infections. Tinea unguium (onychomycosis) is a superficial/cutaneous infection typically treated with oral azoles or terbinafine, not amphotericin B due to its toxicity profile.
All are characteristics of systemic/deep mycosis EXCEPT: Not all systemic fungal infections start in the lungs (e.g., candidiasis can be catheter/GI-related). ---
- Most dimorphic fungi cause the infection
- Pathogenesis mostly occurs due to inhalation of spores
- The most common body part is the lungs for all fungal infections
- Aspergillosis and mucormycosis are systemic mycoses
- Infection can develop in immunocompetent patients
Answer: C.