Total Iron Binding Capacity
Also written as TIBC.
TIBC (Total Iron Binding Capacity): (Increased in IDA)\ni. is a measure of all the proteins in the blood that are available to bind with iron\n(including transferrin).\nii.
What our notes say
- TIBC (Total Iron Binding Capacity): (Increased in IDA)\ni. is a measure of all the proteins in the blood that are available to bind with iron\n(including transferrin).\nii. (Anemia)
- His total serum iron is 130 microgm/dL total iron binding capacity (TIBC) 230 microgm/dL, and soluble serum transferrin receptor is normal. (Hematopathology — Past Paper)
- | Total iron‑binding capacity (TIBC) | Binding capacity of transferrin. | Elevated in deficiency; low/normal in anemia of chronic disease. | (Iron-deficiency anaemia)
- /dL MCV 90 L,Platelet count 250 x 109/L WBC 10 x 109/L Seru iron 10\n\npmol/L. low Total iron-binding capacity of 40 pmol/L Serum ferritin 160 ug/L Thé MOST (HEMAT IMED PAPER)
- and reduced total iron binding capacity (TIBC) and soluble transferrin receptor help to distinguish anaemia of chronic disease from iron (Davidson's Essentials of Medicine - 2nd)
- Serum erythropoietin (prior to red blood cell [RBC] transfusion)\nRBC folate and serum vitamin B-12\nSerum ferritin, iron, and total iron-binding capacity (TIBC)\nThyroid-stimulating hormone (TSH)\nLactate dehydrogenase (LDH)\nHIV testing if clinically indicated (2a MYELODYSPLASIA)
Study material on Total Iron Binding Capacity
- Hematopathology MCQs & Essays: MBChB Exam Revision Guide — Revision Guide
- Iron-deficiency anaemia
- Anemia
- Internal Medicine End of Semester CAT (MBChB 4): haematology and renal, 30 MCQs and 3 short answers
- Haematology End of Year 2025 Past Paper — MKU MBML 3200 Questions & Answers
- Haematology Exam 2025: MCQs on Anaemia, Leukaemia & Clotting
Practice questions on Total Iron Binding Capacity
In iron deficiency, increased total iron-binding capacity is typically associated with which finding?
- Bilirubin
- Iron
- Haptoglobin
- Hemopexin
- Ferritin
Answer: E. Low iron stores (low ferritin) trigger increased transferrin synthesis, raising TIBC.