Toxic Epidermal Necrolysis

Also written as TEN.

Toxic epidermal necrolysis (TEN) is a severe mucocutaneous blistering disease that is usually caused by a drug reaction (see Box 17.9

What our notes say

Toxic epidermal necrolysis (TEN) is a severe mucocutaneous blistering disease that is usually caused by a drug reaction (see Box 17.9 (Davidson's Essentials of Medicine - 2nd)
exclude the differential diagnosis of toxic epidermal necrolysis, (Davidson's Essentials of Medicine - 2nd)
with EB, and in the older child with toxic epidermal necrolysis (Devendra K. Gupta, Krishna M. Goel - Hutchison’s Paediatrics. chdhe-Jaypee Broth)
Severe form (Toxic Epidermal Necrolysis): necrosis extends through full thickness of epidermis (Pathology of Acute Skin Inflammation: Urticaria & Eczema — Notes)
Toxic Epidermal Necrolysis (TEN) — large areas of epidermis slough → fluid loss + secondary infection, similar to burn injuries. (Pathology of Acute Skin Inflammation: Urticaria & Eczema — Notes)
| Hypersensitivity | Rash, Stevens-Johnson syndrome, toxic epidermal necrolysis | (Basic Pharmacology Notes)