Tranexamic Acid
Also written as TXA.
First-line options are the levonorgestrel IUS, tranexamic acid, NSAIDs and combined pills.
What our notes say
- First-line options are the levonorgestrel IUS, tranexamic acid, NSAIDs and combined pills. (Junior Clerkship in Reproductive Health (MBOG 4200): end of year examination, 4 )
- Circulation and haemorrhage control: two large-bore cannulae, send bloods, give a warmed crystalloid bolus (1 to 2 L, Ringer's lactate or saline), then blood transfusion early if there is no response, and tranexamic acid within 3 hours. (General Surgery CAT 2 (MBSG 4600): 4 October 2021)
- Symptom control: NSAIDs and tranexamic acid for heavy bleeding, and iron for anaemia. (Year 4 Gynaecology CAT (MBOG 4212): 13 December 2019)
- Treat the cause (deworming, stop NSAIDs, treat the ulcer, control menstrual bleeding with tranexamic acid or hormones). (Internal Medicine (MBIM 4100) special/supplementary exam, Paper Two: 14 August 2)
- Tranexamic acid (antifibrinolytic) during the period, reducing loss by about half. (Year 6 Gynaecology CAT 1 (MBOG 6511): 13 December 2019, 4 short answers and 16 M)
- Start with uterine massage, empty the bladder and give oxytocin, then tranexamic acid, further uterotonics (misoprostol, ergometrine, carboprost), a balloon tamponade and surgery if bleeding continues. (Obstetrics and Gynaecology Question Bank: 12 Clinical MCQs)