Adenylate Cyclase
Also written as AC.
The alpha-subunit of G-protein activates adenylate cyclase and cAMP is produced
What our notes say
- The alpha-subunit of G-protein activates adenylate cyclase and cAMP is produced (Physio Y1 EOY 2021 — Past Paper Questions & Answers)
- B) The alpha-subunit of G-protein activates adenylate cyclase and cAMP is produced (Endocrine and Metabolic Pathology MCQs: Practice Questions)
- After an incubation of hours to 5 days, cholera toxin activates adenylate cyclase in gut cells, raising cAMP and causing massive secretion of chloride and water. (Internal Medicine CAT 1 (MBIM 6112), 2019/2020: gastroenterology and hepatology,)
- The alpha-subunit of G-protein hydrolyzes GTP and becomes inactive (will no longer bind adenylate cyclase) (Physio Y1 EOY 2021 — Past Paper Questions & Answers)
- Can be cyclized in a reaction catalysed by adenylate cyclase to give cyclic 3',5'-AMP (bchem EOY 2011 — Past Paper Questions & Answers)
- B—false, adenylate cyclase converts ATP (not AMP) to cyclic AMP. (bchem EOY 2011 — Past Paper Questions & Answers)
Study material on Adenylate Cyclase
- LECTURE 2B: Signal Transduction and Second Messengers
- Physio Y1 EOY 2021
- Hypothalamic Hormones: Master Regulators of the Endocrine System