Appendicitis

Pain that starts around the umbilicus and migrates to the right iliac fossa with anorexia and low-grade fever is classic for acute appendicitis.

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Study material on Appendicitis

Practice questions on Appendicitis

A 23-year-old man presents with acute appendicitis that ruptures shortly after admission. He is taken to the operating room for surgery, and postsurgical cultures reveal Escherichia coli and Bacteroides fragilis, susceptibilities pending. Which of the following provides adequate empiric coverage of these two pathogens?

Answer: C. Piperacillin/tazobactam is a β-lactam/β-lactamase inhibitor combination that provides excellent coverage against both gram-negative aerobes (E. coli) and anaerobes (Bacteroides fragilis). While the other agents cover E. coli, only piperacillin/tazobactam provides adequate coverage against Bacteroides species, which are common in intra-abdominal infections. ---

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