Bullous Pemphigoid

Also written as BP.

Bullous pemphigoid (BP) is the most common immunobullous

What our notes say

Bullous pemphigoid (BP) is the most common immunobullous (Davidson's Essentials of Medicine - 2nd)
Tense bullae, negative Nikolsky sign (subepidermal split), and linear IgG along the basement membrane are all classic for bullous pemphigoid, distinguishing it from pemphigus vulgaris (intraepidermal, Nikolsky positive). (Skin & Breast Pathology MCQs: Dermatological Lesions & Diseases — MCQ Bank)
necrolysis).\nSubepidermal split: Tense-roofed blisters occur (e.g. bullous pemphigoid, Fig. (Davidson's Essentials of Medicine - 2nd)
Bullous pemphigoid autoantibodies target hemidesmosomal proteins (BP180/BP230) at the dermoepidermal junction, causing subepidermal blistering. (Skin & Breast Pathology MCQs: Dermatological Lesions & Diseases — MCQ Bank)
Compare and contrast pemphigus vulgaris and bullous pemphigoid under pathogenesis, morphology, and clinical presentation. (Exam Prep: Skin Infections, Psoriasis & Pemphigus — Notes)
| Blistering | Pemphigus group, Bullous Pemphigoid, Dermatitis Herpetiformis, EB, Porphyria | Anti-desmoglein (suprabasal) vs anti-BPAG2 (subepidermal, tense) vs celiac-linked granular IgA | (Exam Prep: Skin Infections, Psoriasis & Pemphigus — Notes)