Gastric Cancer

The prognosis with early gastric carcinoma (EGC) is good, compared with other gastric cancers.

What our notes say

• The prognosis with early gastric carcinoma (EGC) is good, compared with other gastric cancers. (Gastrointestinal and liver — Past Paper Questions & Answers)
• Cytotoxin-associated gene A (CagA): Injected into host cells via a type IV secretion system, it interferes with cell signaling pathways, promotes inflammation, and is associated with increased risk of gastric cancer. (Gi sem2 patho — Past Paper Questions & Answers)
• *Only a small minority of infected individuals ever develop gastric cancer or MALT lymphoma — 97% is a vast overstatement.* (Oncopathology MCQs: Test Your Knowledge on Cancer Pathology)
• It is a major cause of pernicious anaemia and increases gastric cancer risk. (GASTROINTESTINAL PATHOLOGY (Part 1))
• Transcoelomic (peritoneal) spread: across body cavities, for example ovarian and gastric cancer (Krukenberg tumour). (General Surgery CAT 2 (MBSG 4600): 4 October 2021)
• Differential diagnosis: bleeding oesophageal or gastric varices (portal hypertension), peptic ulcer (NSAIDs, H. pylori), erosive gastritis, Mallory-Weiss tear, oesophagitis, gastric cancer, portal hypertensive gastropathy, and a coagulopathy from liver disease. (Internal Medicine (MBIM 4100) special/supplementary exam, Paper Two: 14 August 2)

Related topics

• Temporalis
• Hernia
• Peritonitis
• Thyroid Cancer
• Lymphoma
• Cervical Cancer
• Hepatocellular Carcinoma
• Ulcerative Colitis
• Iron Deficiency Anaemia
• Varicose Veins