Glomerular Filtration Rate
Also written as GFR.
The best marker for glomerular filtration rate (GFR) is:
What our notes say
- The best marker for glomerular filtration rate (GFR) is: (Chemical Pathology MCQs: Clinical Chemistry, Endocrine & Renal)
- Acute Renal Failure (ARF), now commonly referred to as Acute Kidney Injury (AKI), is a sudden decline in renal function, leading to decreased glomerular filtration rate (GFR), retention of waste products, fluid imbalance, and electrolyte disturbances. (CLINICAL BIOCHEMISTRY LAQs & SAQs)
- During normal pregnancy the glomerular filtration rate can increase by as much as: (Reproductive Health 1 End of Trimester CAT: 40 MCQs and 4 short answers)
- Serum Creatinine*Implication*: Elevated levels indicate impaired renal function or reduced glomerular filtration rate (GFR). (CLINICAL BIOCHEMISTRY LAQs & SAQs)
- Restore blood volume to normalize blood pressure and glomerular filtration rate (GFR). (Liver Function Tests (LFTs))
- Glomerular Filtration Rate (GFR): The best overall indicator of kidney function. (Endocrine & Renal Pathology — Must Know Notes)
Study material on Glomerular Filtration Rate
- CLINICAL BIOCHEMISTRY LAQs & SAQs
- Liver Function Tests (LFTs)
- Endocrine & Renal Pathology — Must Know Notes
- Chemical path 2021
- Chemical Pathology MCQs: Clinical Chemistry, Endocrine & Renal
- Chemical Pathology Practice Examination
- Chemical Path, Long Answer and Short Answer
- Chemical Pathology MCQs
- Weekly Year 2: Physiology Exam - May 29, 2026 (Section A: MCQs)
- Weekly Year 2: Physiology Exam - May 15, 2026 (Sections B & C)
- Medical Physiology Paper I MCQs
- Chemical Pathology MCQs
- Weekly Year 2: Physiology Exam - May 15, 2026 (Section A: MCQs)
Practice questions on Glomerular Filtration Rate
Which of the following would cause an increase in both glomerular filtration rate (GFR) and renal plasma flow (RPF)?
- constriction of the efferent arteriole
- dilation of the afferent arteriole
- constriction of the afferent arteriole
- dilation of the efferent arteriole
- Usually mediated by non-specific mechanisms
Answer: B. Afferent arteriole dilation increases both blood flow into the glomerulus (increasing RPF) and glomerular capillary pressure (increasing GFR). This is the only option that increases both parameters. ---
Glomerular filtration rate would be increased by
- Constriction of the afferent arteriole
- A decrease in afferent arteriolar pressure
- Compression of the renal capsule
- A decrease in the concentration of plasma protein
- A decrease in renal blood flow
Answer: D. Decreased plasma protein concentration reduces oncotic pressure, decreasing the force opposing filtration and thereby increasing GFR. ---
The best marker for glomerular filtration rate (GFR) is
- Serum creatinine
- Blood urea nitrogen (BUN)
- Creatinine clearance
- Serum cystatin C Correct
- Serum cystatin C
Answer: D. Cystatin C is less affected by muscle mass, age, and diet compared to creatinine, providing a more accurate GFR assessment. ---
Which of the following would cause an increase in both glomerular filtration rate (GFR) and renal plasma flow (RPF)?
- Dilation of the afferent arteriole
- Constriction of the efferent arteriole
- Constriction of the afferent arteriole
- Dilation of the efferent arteriole
Answer: A. Dilation of the afferent arteriole increases glomerular capillary hydrostatic pressure, which directly increases GFR. It also increases blood flow into the glomerulus, thus increasing RPF. Constriction of the efferent arteriole would increase GFR but decrease RPF. Constriction of the afferent arteriole would decrease both GFR and RPF.
Which of the following would cause an increase in both glomerular filtration rate (GFR) and renal plasma flow (RPF)?
- Dilation of the afferent arteriole
- Constriction of the efferent arteriole
- Constriction of the afferent arteriole
- Dilation of the efferent arteriole
Answer: A. Dilation of the afferent arteriole increases glomerular capillary hydrostatic pressure, which directly increases GFR. It also increases blood flow into the glomerulus, thus increasing RPF. Constriction of the efferent arteriole would increase GFR but decrease RPF. Constriction of the afferent arteriole would decrease both GFR and RPF.
Which of the following would cause an increase in both glomerular filtration rate (GFR) and renal plasma flow (RPF)?
- Constriction of the afferent arteriole
- Dilation of the efferent arteriole
- Constriction of the efferent arteriole
- Dilation of the afferent arteriole
Answer: D. Dilation of the afferent arteriole increases blood flow into the glomerulus, which increases both GFR and RPF, assuming other factors remain constant. Constriction of the efferent arteriole would increase GFR but decrease RPF.