Hageman Factor
Also written as XII.
Kinin system — activation of the Hageman factor (Factor XII) generates bradykinin via kallikrein, causing vasodilatation, increased permeability and pain.
What our notes say
- Kinin system — activation of the Hageman factor (Factor XII) generates bradykinin via kallikrein, causing vasodilatation, increased permeability and pain. (General & Systemic Pathology SAQ Paper II — 15 July 2025 (MBPA 3500, MKU Year 3,)
- Kinin system — Hageman factor (XII) activates → kallikrein → Bradykinin (↑permeability, pain, vasodilation) (General & Systemic Pathology SAQ — Paper II)
- | XII | Hageman Factor | Intrinsic | Initiates intrinsic (contact activation) pathway | (Haemostasis & Coagulation: Platelet Function & Bleeding Disorders)
- Hageman factor = Factor XII — initiates intrinsic pathway (Haemostasis & Coagulation: Platelet Function & Bleeding Disorders)