Liddle'S Syndrome
Intrinsic ARF, 372, 374, 382 Kinins, 68 Liddle’s syndrome, 404
Liddle's Syndrome
- Features : Hypertension, hypokalemia, low renin/aldosterone
- Mechanism : ↑ENaC channels in distal tubule
- Inheritance : Autosomal dominant
Read this in KIDNEY FUNCTION TESTS & GASTRIC FUNCTION — Notes
Liddle’s Syndrome (Pseudohyperaldosteronism)
- Hypertension, hypokalemic metabolic alkalosis .
- Low renin & aldosterone .
- Due to excess Na⁺ reabsorption (ENaC channel defect) .
Read this in Liver Function Tests (LFTs) — Notes
What our notes say
- Intrinsic ARF, 372, 374, 382 Kinins, 68 Liddle’s syndrome, 404 (Harrisons Pulmonary and Critical Care Medicine)
- \ncalcium channel blockers, 399t, 401 for hypertensive emergencies, 465t, 466 Liddle’s syndrome\nenhanced external counterpulsation, 406 for ischemic heart disease, 399t clinical features of, 456t\nexplanation and reassurance, 396 Laboratory tests. (Harrisons Cardiovascular Medicine 2nd Edition 2)