Luteinizing Hormone
Also written as LH.
Regulation: This entire initial process, particularly the activity of StAR and P450scc, is significantly stimulated by trophic hormones such as Luteinizing Hormone (LH) and Adrenocorticotropic Hormone (ACTH), acting through the cAMP/PKA pathway.
What our notes say
- Regulation: This entire initial process, particularly the activity of StAR and P450scc, is significantly stimulated by trophic hormones such as Luteinizing Hormone (LH) and Adrenocorticotropic Hormone (ACTH), acting through the cAMP/PKA pathway. (Steroid and Sex Hormones)
- X (sharp, tallest peak exactly at day 14): luteinizing hormone (LH) — the LH surge that triggers ovulation (Aponeurosis — Embryology Question Bank)
- LH (Luteinizing hormone): Stimulates Leydig cells to secrete testosterone, which further promotes spermatogenesis. (MEDICAL PHYSIOLOGY II ESsays)
- Luteinizing Hormone (LH):In females, triggers ovulation and the formation of the corpus luteum, which secretes progesterone. (MEDICAL PHYSIOLOGY II ESsays)
- Ovulation (Day 14):Triggered by a surge in LH (Luteinizing Hormone). (Medical Physiology Pp2 Year 2)
- It stimulates the gonadotroph cells in the anterior pituitary to release Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH). (Hypothalamic Hormones: Master Regulators of the Endocrine System)
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Practice questions on Luteinizing Hormone
Actions of Luteinizing hormone in the male include:
- Stimulating mitosis in spermatogonia
- Initiating spermatogenesis by stimulating seminiferous tubule epithelial cells
- Migration of spermatocytes into seminiferous tubular lumen and onward transmission
- Development of the follicles ✅ Answer: B. Initiating spermatogenesis by stimulating seminiferous tubule epithelial cells
Answer: A. Initiating spermatogenesis by stimulating seminiferous tubule epithelial cells is the physiologically correct answer per standard MBChB-level teaching on this topic. ---