Androgen Insensitivity Syndrome

Also written as AIS.

The findings point to the rare testicular feminization (androgen insensitivity syndrome), with a karyotype of 46, XY.

What our notes say

• The findings point to the rare testicular feminization (androgen insensitivity syndrome), with a karyotype of 46, XY. (Female system — Past Paper Questions & Answers)
• Androgen insensitivity syndrome: 46,XY karyotype, tissues cannot respond to androgens → phenotypically female external appearance, primary amenorrhea, presents in adolescence. (Clinical Genetics: Master Mendelian Disorders & Molecular Basis)
• Androgen Insensitivity Syndrome (AIS) / Testicular Feminizing Syndrome (5 marks) (Medical Physiology Year Two – Paper Two MCQs)
• Androgen Insensitivity Syndrome (AIS): Genetic defect in androgen receptors, causing XY individuals to develop female external genitalia despite normal or high testosterone levels. (Steroid and Sex Hormones)

Study material on Androgen Insensitivity Syndrome

• Medical Physiology Year Two – Paper Two MCQs

Related topics

• Luteinizing Hormone
• Follicle-Stimulating Hormone
• Androgen Receptor
• Congenital Adrenal Hyperplasia
• Cortisol
• Aldosterone
• Pituitary Gland
• Menstrual Cycle
• Rickets
• Genetic Disorders