Androgen Receptor

Also written as AR.

DHT is 10x more potent than testosterone in binding androgen receptors.

What our notes say

• DHT is 10x more potent than testosterone in binding androgen receptors. (Male Reproductive System Pathology)
• DHT is 10x more potent than testosterone in binding androgen receptors (Penile & Testicular Pathologies: Hypospadias, Tumors, Torsion – Male Reproductiv)
• Androgen receptor (AR) signalling drives growth throughout the disease course, including castration-resistant stage (Female & Male Genital Pathology: Ulcers, HPV, Endometriosis, Pre-eclampsia)
• DHT (from testosterone via 5-alpha-reductase type 2) binds nuclear androgen receptors → promotes growth (Quick Guide: Male Reproductive System Pathology, Testis, Penis)
• | SBMA | LMN weakness · diminished androgen | Androgen receptor (polyglutamine) | Androgen receptor | (Neurodegenerative Prion Diseases: CJD, Pathology & Rapid Dementia)
• Antiandrogens: Bicalutamide, Enzalutamide — block androgen receptor. (Cancer Pharmacology: Cell Cycle, Oncogenes & Drug Targets)

Study material on Androgen Receptor

• Medical Physiology Year Two – Paper Two MCQs

Related topics

• Male Reproductive
• Chronic Nonbacterial
• Testicular Torsion
• Prostate Cancer
• Male Reproductive System Pathology
• Male Reproductive System
• Benign Prostatic Hyperplasia
• Testis
• Androgen Insensitivity Syndrome
• Hydronephrosis