Oncogenic Viruses
Hep B liver damage is mostly immune-mediated, not direct viral killing), cell transformation (oncogenic viruses push cells toward malignancy instead of killing them)
Oncogenic Viruses (Viral Carcinogenesis)
- Key terms — distinguish clearly for exam :
- Carcinogenesis – the overall multi-step process by which normal cells become cancerous
- Oncogenesis – specifically the development of a tumor through activation of oncogenes/inactivation of tumor suppressor genes
- Tumorigenesis – the formation and progression of a tumor mass
- How viruses cause cancer (general mechanisms — important for essay answers) :
Read this in Medical Virology: Hepatitis, Viral Carcinogenesis & Oncogenic Viruses
What our notes say
- Hep B liver damage is mostly immune-mediated, not direct viral killing), cell transformation (oncogenic viruses push cells toward malignancy instead of killing them) (VIROLOGY SEM 3 CRASHED)
- HPV is one of the most significant oncogenic viruses in human medicine — responsible for virtually all cases of cervical cancer and many other anogenital and oropharyngeal malignancies. (EXAM: Bacteriophages, Laboratory Diagnosis, HPV & Parvovirus B19)
- Say "continue" when you're ready for Section 2 (RNA viruses → Hepatitis → Arboviruses → Oncogenic viruses → Encephalitis/Hemorrhagic fevers → HIV). (VIROLOGY SEM 3 CRASHED)
- *Covers: Hepatitis Viruses → Oncogenic Viruses → Arboviruses → HIV (everything after the Mid-Term CAT)* (Medical Virology: Hepatitis, Viral Carcinogenesis & Oncogenic Viruses)
- Immunosuppression – some oncogenic viruses act mainly by suppressing host immunity, allowing other oncogenic processes to proceed unchecked (e.g. (Medical Virology: Hepatitis, Viral Carcinogenesis & Oncogenic Viruses)
- Hepatitis Viruses, Oncogenic Viruses, Paramyxoviruses & Arboviruses (EXAM: Hepatitis Viruses, Oncogenic Viruses, Paramyxoviruses & Arboviruses)
Study material on Oncogenic Viruses
- EXAM: Hepatitis Viruses, Oncogenic Viruses, Paramyxoviruses & Arboviruses
- Medical Virology: Hepatitis, Viral Carcinogenesis & Oncogenic Viruses
- VIROLOGY SEM 3 CRASHED
Practice questions on Oncogenic Viruses
The following are oncogenic viruses in humans EXCEPT ---
- Human Papilloma Virus (HPV)
- Epstein Barr Virus (EBV)
- Hepatitis B virus
- Polio Virus
Answer: D.