Wound Healing
Wound healing is affected by all of the following EXCEPT
WOUND HEALING (asked repeatedly in multiple forms — master fully)
- Sequence of cutaneous wound healing:
- Haemostasis — blood clot formation (first event)
- Inflammation — neutrophils then macrophages clear debris
- Proliferation — granulation tissue forms (fibroblasts + macrophages + new capillaries/angiogenesis), re-epithelialisation occurs
- Remodelling — collagen type III replaced by stronger type I, scar matures, wound contracts
Read this in General Pathology Revision: Cell Injury, Inflammation & Adaptation (MBPA 3500 Pa
What our notes say
- Wound healing is affected by all of the following EXCEPT (General Pathology I)
- The following events are common to primary and secondary wound healing EXCEPT (General Pathology)
- The following events are common to primary and secondary wound healing EXCEPT: (Medical MCQs: Chemical Pathology & Haematology Exam Review)
- • Indicators of poor nutrition – temporalis muscle wasting, cracked skin, loss of scalp and body hair and poor wound healing. (General examination (2) — Past Paper Questions & Answers)
- Complications of cutaneous wound healing include ONE of the following (Pathology Continuous Assessment July 2021)
- Wound healing involves all the processes outlined below EXCEPT (General Pathology I)
Study material on Wound Healing
- Medical MCQs: Chemical Pathology & Haematology Exam Review
- general Pathology Q&A
- Medical Pathology Final Revision: Chemical, Hema, Systemic
- General Pathology
- General Pathology I
- General Pathology
- General Pathology Revision: Cell Injury, Inflammation & Adaptation (MBPA 3500 Paper 1)
- Cat. Pathology: Acute Inflammation, Mediators & Pulmonary Embolism
- General Pathology I
- General & Systemic Pathology Exam: MBChB Year 3 Questions
- General Pathology
- Weekly Year 1: Enzymes, Vitamins and Minerals Exam - June 19, 2026 (Section A: MCQs)
- Weekly Pathology Exam - March 13, 2026 (Section A: MCQs)
Practice questions on Wound Healing
A 55-year-old diabetic develops a foot ulcer that fails to heal despite antibiotics. Which factor is LEAST likely contributing to impaired wound healing?
- Reduced oxygen delivery due to peripheral vascular disease
- Neuropathy preventing protective sensations
- Systemic metabolic abnormalities affecting cellular function
- Excessive neutrophil extracellular trap formation
- Secondary bacterial infection
Answer: D. Diabetic ulcers result from multiple factors: ischemia from vascular disease (atherosclerosis) reduces oxygen delivery needed for healing; neuropathy removes protective pain sensation allowing continued trauma; metabolic abnormalities (hyperglycemia, insulin resistance) impair cellular functions; and the wounds are prone to infection. These are all documented contributors. NET formation, while it can occur in infecti
A patient presents with bleeding gums, impaired wound healing, and petechiae. These symptoms are most consistent with a deficiency in which vitamin?
- A. Vitamin A
- B. Vitamin D
- C. Vitamin C
- D. Vitamin K
Answer: C. These symptoms are classic signs of scurvy, caused by a deficiency of Vitamin C (Ascorbic Acid). Vitamin C is crucial for collagen synthesis, acting as a cofactor for hydroxylase enzymes involved in forming stable collagen helices.
Which trace mineral functions as a cofactor for numerous enzymes, supports immune function, and is involved in wound healing?
- A. Manganese
- B. Chromium
- C. Fluoride
- D. Zinc
Answer: D. Zinc is an essential trace mineral that acts as a cofactor for over 300 enzymes involved in diverse metabolic processes. It plays crucial roles in immune function, wound healing, DNA synthesis, and cell division.
Wound healing is affected by all of the following EXCEPT:
- Nutrition
- Infection
- Glucocorticoids
- Blood group of the patient
Answer: D. Vitamin C deficiency (nutrition), infection, and steroids (glucocorticoids) significantly impair healing. Blood group (A, B, O) has no impact on the healing process.
Wound healing is affected by all of the following EXCEPT:
- Nutrition (Vitamin C)
- Blood supply
- Infection
- Gender of the patient
Answer: D. Major factors affecting wound healing include nutritional status, local infection, and vascular adequacy, but patient gender is generally not a primary factor.
Wound healing involves all the processes outlined below EXCEPT:
- Inflammation
- Proliferation (granulation tissue)
- Remodeling
- Metaplasia
Answer: D. The three phases of wound healing are inflammation, proliferation, and maturation/remodeling. Metaplasia is a cellular adaptation, not a step in normal healing.