Venous Thromboembolism
Also written as VTE.
| Clotting | Factors V, VII, VIII, IX, X, XII, von Willebrand factor and fibrinogen (doubles) rise; antithrombin III and protein S fall; fibrinolysis is reduced | A hypercoagulable state: protects against postpartum haemorrhage but raises the risk of venous thromboembolism |
Treatment at a glance
- Start anticoagulation at once if suspicion is high: a DOAC (rivaroxaban or apixaban)
- Where DOACs are unavailable: enoxaparin, overlapped with warfarin until the INR is 2–3 for two days
What our notes say
- | Clotting | Factors V, VII, VIII, IX, X, XII, von Willebrand factor and fibrinogen (doubles) rise; antithrombin III and protein S fall; fibrinolysis is reduced | A hypercoagulable state: protects against postpartum haemorrhage but raises the risk of venous thromboembolism | (Physiological changes in pregnancy)
- This is his first episode of venous thromboembolism (VTE). (Haematology paper 1 Past Papers — Past Paper Questions & Answers)
- Deep Vein Thrombosis and Venous Thromboembolism (with Pulmonary Embolism) — Year 4 Internal Medicine Notes (DVT and Venous Thromboembolism (with Pulmonary Embolism))
- Venous thromboembolism (VTE) = DVT + PE: one disease with two faces. (DVT and Venous Thromboembolism (with Pulmonary Embolism))
- Other contraindications include smoking over age 35, a history of venous thromboembolism and uncontrolled hypertension. (Obstetrics and Gynaecology Question Bank: 12 Clinical MCQs)
- Result: venous thromboembolism — deep vein thrombosis and pulmonary embolism (Haemostasis & Coagulation: Platelet Function & Bleeding Disorders)