Molecular Genetics
Are there any molecular genetic tests that might guide your choice of therapy? (9 marks)
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Study material on Molecular Genetics
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Practice questions on Molecular Genetics
What is functional cloning (classic approach) in molecular genetics?
- Random gene isolation
- Starting with known affected protein to isolate and clone normal gene
- Mapping disease to chromosome location
- Gene therapy technique
- Usually mediated by non-specific mechanisms
Answer: B. Functional cloning starts with a known affected protein (clinical phenotype), then isolates and clones the normal gene, and determines molecular changes affecting the gene. ---