Non-Hodgkin Lymphoma
Also written as NHL.
Though indolent, this kind of non-Hodgkin lymphoma is difficult to eradicate.
What our notes say
- Though indolent, this kind of non-Hodgkin lymphoma is difficult to eradicate. (hematopathology — Past Paper Questions & Answers)
- A monoclonal antibody against CD20, a B cell surface antigen, is used for treatment of certain non-Hodgkin lymphomas (Oncopathology MCQs: Test Your Knowledge on Cancer Pathology)
- Non-Hodgkin lymphoma is the most common testicular tumor in men older than 60 (General Pathology MCQs: Fixatives, FNA, Endocrine & ARDS)
- Follicular Lymphoma is a prevalent adult non-Hodgkin lymphoma defined by the t(14;18) translocation leading to BCL2 overexpression and a nodular proliferation of neoplastic germinal center B cells. (White Cell Disorders — Must-Know Notes)
- Hodgkin Lymphoma is distinct from non-Hodgkin lymphomas due to the presence of Reed-Sternberg (RS) giant cells and its predictable contiguous spread pattern, which allows for local therapy in early stages. (White Cell Disorders — Must-Know Notes)
- Non-Hodgkin Lymphoma (NHL) is a diverse group of clonal lymphoid tumors. (Non-Hodgkin Lymphoma: Classification, Symptoms, Diagnosis, and Treatment)
Study material on Non-Hodgkin Lymphoma
- Non-Hodgkin Lymphoma: Classification, Symptoms, Diagnosis, and Treatment
- Chemical pathology and Endocrine pathology
- White Cell Disorders — Must-Know Notes
- hematopathology
- Gastrointestinal and liver
- Oncopathology MCQs: Test Your Knowledge on Cancer Pathology
- Non-Hodgkin Lymphoma: Classification, Symptoms, Diagnosis, and Treatment — Practice Questions
- Non-Hodgkin Lymphoma: Classification, Symptoms, Diagnosis, and Treatment — Practice Questions
- Non-Hodgkin Lymphoma: Classification, Symptoms, Diagnosis, and Treatment — Practice Questions
- Non-Hodgkin Lymphoma: Classification, Symptoms, Diagnosis, and Treatment — Practice Questions
- Non-Hodgkin Lymphoma: Classification, Symptoms, Diagnosis, and Treatment — Practice Questions
- Non-Hodgkin Lymphoma: Classification, Symptoms, Diagnosis, and Treatment — Practice Questions
Practice questions on Non-Hodgkin Lymphoma
What percentage of Non-Hodgkin Lymphomas are of B-cell origin?
- 70%
- 75%
- 85%
- 90%
Answer: C. NHL is 85% B-cell and 15% T/NK-cell origin. This is a foundational fact frequently tested. ---
What percentage of Non-Hodgkin Lymphomas are of B-cell origin?
- 20-30%
- 50%
- 85-90%
- 99%
Answer: C. Approximately 85% to 90% of NHLs are of B-cell origin, with the remainder being T-cell or NK-cell lymphomas. ---
What is the incidence of Non-Hodgkin Lymphoma per 100,000 population?
- 1-2 per 100,000
- 15-20 per 100,000
- 50-60 per 100,000
- 100 per 100,000
Answer: B. The incidence of NHL is approximately 15-20 per 100,000, making it significantly more common than Hodgkin lymphoma. ---
True statement about staging of non-Hodgkin's lymphoma?
- Stage I & II confined above diaphragm
- All stages similar prognosis
- Burkitt's classified as ALL-L3
- CT scan used in imaging
Answer: D. CT scanning is standard for staging NHL; Burkitt's is a B-cell lymphoma, and stages have very different prognoses. ---
True statement concerning staging of non-Hodgkin's lymphoma? ---
- Stage I and II are only confined superior to the diaphragm
- All stages have similar prognosis
- Burkitt's lymphoma is classified as ALL-L3
- CT scan is used in imaging studies CT is standard for staging. (A and B are false; C describes FAB classification, not staging.)
Answer: A.