Nucleotide Excision Repair

Also written as NER.

Xeroderma pigmentosum is caused by mutations in genes responsible for nucleotide excision repair (NER).

What our notes say

• Xeroderma pigmentosum is caused by mutations in genes responsible for nucleotide excision repair (NER). (Defects in DNA Repair and Replication)
• If NERM (Nucleotide Excision Repair Mechanism) is defective, it leads to xeroderma pigmentosum (XP). (Types of Mutations in ARBHN (Amino Acid Replacement Based on Hemoglobin to Produ)
• UV radiation → forms pyrimidine dimers in DNA, normally repaired by nucleotide excision repair (Genetic Disorders Pathology Crash Course: Exam Revision Notes)
• Xeroderma pigmentosum — inherited defect in nucleotide excision repair → greatly increased skin cancer risk (Genetic Disorders Pathology Crash Course: Exam Revision Notes)
• | Xeroderma pigmentosum | Nucleotide excision repair (NER) | Cannot repair UV-induced pyrimidine dimers | Skin cancers | (Hallmarks of Cancer: Molecular Basis, Cell Cycle & Oncogenes)
• Involved in nucleotide excision repair (NER), a DNA repair mechanism that corrects transcription errors. (Transcription Factors)

Study material on Nucleotide Excision Repair

• Types of Mutations in ARBHN (Amino Acid Replacement Based on Hemoglobin to Product Form)
• Transcription Factors
• Hallmarks of Cancer: Molecular Basis, Cell Cycle & Oncogenes
• Transcription Factors and Gene Regulation

Related topics

• Defects in DNA Repair
• Alkylating Agents
• Genetic Disorders
• Gene Expression
• Microsatellite Instability
• DNA Replication
• Duchenne Muscular Dystrophy
• Carcinogenesis
• Hallmarks of Cancer
• Transcription Factors