Tumour Markers
*CA 125 is the standard tumour marker used for monitoring epithelial ovarian cancer (though not specific enough for screening).*
What our notes say
- *CA 125 is the standard tumour marker used for monitoring epithelial ovarian cancer (though not specific enough for screening).* (Oncopathology MCQs: Test Your Knowledge on Cancer Pathology)
- *Tumour markers are biochemical/serologic assays (e.g., blood tests), not tests that assess tissue morphology under the microscope like the others.* (Oncopathology MCQs: Test Your Knowledge on Cancer Pathology)
- Tumour markers (CA-125, AFP, hCG, LDH) to select who needs surgery. (Year 4 Gynaecology CAT 1 (MBOG 4212): 2 July 2021)
- Q82: Identify the gland, name a tumour marker, list two components, and name two ovarian hormones with their sources (Aponeurosis — Histology Question Bank)
- Tumour markers (CA 19-9) — elevated in pancreatic/biliary malignancy (Medical MCQs: Chemical Pathology & Haematology Exam Review)
- Tumour markers: CA-125 (epithelial, monitoring not screening — poor specificity), AFP (yolk sac), β-hCG (choriocarcinoma), inhibin (granulosa cell) (Ovarian & Colorectal Cancer: Risks, Pathogenesis, Staging)
Study material on Tumour Markers
- Molecular Basis of Cancer: Cell Cycle, Apoptosis & Angiogenesis
- Oncopathology MCQs: Test Your Knowledge on Cancer Pathology
- CRUSH COURSE YEAR 3 SEM 1 WORK (Part 1)
- Oncopathology & Histopathology Answers
Images
Practice questions on Tumour Markers
Which laboratory test is most widely used as a prognostic tumour marker in lymphoma?
- C-reactive protein
- Beta-2 microglobulin
- Lactate dehydrogenase
- Erythrocyte sedimentation rate
Answer: C. Serum LDH reflects tumour burden and turnover and is incorporated into prognostic indices such as the International Prognostic Index for lymphoma. ---
Which tumour marker for ovarian cancer?
- CA 125
- CA 15.3
- CA 19.9
- CEA
Answer: A. CA 125 is the primary tumor marker used for ovarian cancer detection and monitoring. ---