Uterine Leiomyoma

Definition: Uterine leiomyomas (fibroids) are benign smooth muscle tumors of the uterus, representing the most common gynecologic tumor.

Uterine Leiomyomas (Fibroids) (×2)

Bisected uterus with multiple well-circumscribed whorled whitish nodular masses
Uterine leiomyomata (fibroids) — most common benign smooth muscle tumour of the uterus
Multiple well-circumscribed rounded nodules within myometrium
Whorled, white-tan cut surface
Clear demarcation from surrounding myometrium (pseudocapsule)

Well-circumscribed, whorled, white, firm masses arising from myometrial smooth muscle
Classified by location: submucosal, intramural, subserosal
Oestrogen-dependent — grow during reproductive years, regress after menopause
degenerative changes leiomyomas can undergo:
Hyaline degeneration — most common type

Definition: Uterine leiomyomas (fibroids) are benign smooth muscle tumors of the uterus, representing the most common gynecologic tumor. (General Pathology Q&A)
Outline the morphologic features of Uterine leiomyoma (5 Marks) (Medical MCQs: Chemical Pathology & Haematology Exam Review)
State 5 degenerative changes uterine leiomyomas can undergo. (Female & Male Genital Pathology: Ulcers, HPV, Endometriosis, Pre-eclampsia)
State 5 degenerative changes uterine leiomyomas can undergo. — See section 4. (General Pathology Revision: Cell Injury, Inflammation & Adaptation (MBPA 3500 Pa)
Outline the morphologic features of Uterine Leiomyoma. — See section 4 (morphology subsection). (General Pathology Revision: Cell Injury, Inflammation & Adaptation (MBPA 3500 Pa)