Platelet Activating Factor
Also written as PAF.
Platelet-activating factor (PAF) is produced during inflammation.
What our notes say
- Platelet-activating factor (PAF) is produced during inflammation. (Inflammation and Tissue Repair — MCQ Bank)
- Platelet-activating factor, an ether-linked, inflammation-induced injury. (Harrisons Pulmonary and Critical Care Medicine)
- Contain platelet activating factor acetyle hydrolase & IL-l 0 which protect\nagainst NEC. (BABY NELSON PEADS)
- -¢- Platelet activating factor, tumor necrosis factor and cytokines may play role in\nbowel necrosis. (BABY NELSON PEADS)
- Platelet-activating factor (PAF) — platelet aggregation, vasodilatation/permeability, leukocyte activation. (General & Systemic Pathology SAQ Paper II — 15 July 2025 — Past Paper)
- Platelet-activating factor (PAF): potent phospholipid mediator → platelet aggregation, bronchoconstriction, vasodilation, key role in inflammatory/allergic responses (Pharmacology CRASH Course — Notes)
Study material on Platelet Activating Factor
- Harrisons Pulmonary and Critical Care Medicine
- Inflammation and Tissue Repair — MCQ Bank
- General pathology
- Biochemistry End-of-Year 2015
- Pharmacology CRASH Course — Notes
- Pharmacology Examination MCQs
Practice questions on Platelet Activating Factor
: Platelet Activating Factor (PAF) is chemically classified as a
- Protein
- Steroid
- Phospholipid
- Amino acid derivative
Answer: C. PAF is chemically acetyl-glyceryl-ether-phosphocholine, making it a phospholipid derivative. Despite its small size compared to eicosanoids, it has potent biological activities including platelet aggregation, inflammation, and increased vascular permeability at very low concentrations (nanomolar range).