Renal Blood Flow
Also written as RBF.
| Renal blood flow (RBF) autoregulation – myogenic response + tubuloglomerular feedback (TGF) maintains GFR between MAP ≈ 80‑180 mmHg | When MAP falls below the autoregulatory range, afferent arteriolar dilation is insufficient → ↓RBF → ↓GFR (pre‑renal).
What our notes say
- | Renal blood flow (RBF) autoregulation – myogenic response + tubuloglomerular feedback (TGF) maintains GFR between MAP ≈ 80‑180 mmHg | When MAP falls below the autoregulatory range, afferent arteriolar dilation is insufficient → ↓RBF → ↓GFR (pre‑renal). (Acute kidney injury)
- Renal blood flow and GFR rise by 40 to 50%, so urea and creatinine fall and glycosuria can occur. (Reproductive Health 1 End of Trimester CAT: ectopic pregnancy, ANC and abortion )
- Renal blood flow and GFR rise by 40 to 50%, and the renal pelvis and ureters dilate (more on the right). (Obstetrics II CAT: miscarriage, pregnancy physiology and antenatal care, 26 MCQs)
- | Lymphatic drainage of abdomen | Ascites contributes to intra‑abdominal pressure, further impairing renal blood flow | (Hepatorenal syndrome)
- | Splanchnic vasoconstriction | Terlipressin (vasopressin analogue) or midodrine + octreotide | Reduces portal inflow, raises systemic vascular resistance, improves renal blood flow. | (Hepatorenal syndrome)
- COX-1 – constitutive, "housekeeping" (gastric mucosal protection, platelet thromboxane production, renal blood flow) (Pharmacology CRASH Course)