Sickle Cell Anaemia
Also written as SS.
Sickle-cell anaemia has mortality of 15%\nby the age of 20 yrs and 50% by the age of 40 yrs.\nThe thalassaemias\nThe thalassaemias are a group of inherited disorders of Hb produc tion in which there is impaired synthesis of alpha or beta globin\nchains.
What our notes say
- Sickle-cell anaemia has mortality of 15%\nby the age of 20 yrs and 50% by the age of 40 yrs.\nThe thalassaemias\nThe thalassaemias are a group of inherited disorders of Hb produc tion in which there is impaired synthesis of alpha or beta globin\nchains. (Davidson's Essentials of Medicine - 2nd)
- Some others are considered in other\nFor example, the haemoglobin in sickle-cell anaemia (HbS) (Devendra K. Gupta, Krishna M. Goel - Hutchison’s Paediatrics. chdhe-Jaypee Broth)
- Sickle cell Anaemia- hemoglobin synthesis disorder whereby chains are abnormal but (Medical Physiology Assorted SAQs — With Answers (Past Paper Study Guide))
- Sickle cell anaemia is the textbook example — Glu→Val substitution at codon 6 of beta-globin (Clinical Genetics: Master Mendelian Disorders & Molecular Basis — Notes)
- With careful\nsupervision and the use of blood transfusion many children\nwith sickle cell anaemia (SS) reach adult life. (Devendra K. Gupta, Krishna M. Goel - Hutchison’s Paediatrics. chdhe-Jaypee Broth)
- | Examples | Huntington disease, Marfan syndrome, familial hypercholesterolemia, achondroplasia, polycystic kidney disease | Cystic fibrosis, phenylketonuria, sickle cell anaemia, Tay-Sachs disease, galactosemia | (Genetic Disorders CAT: Key Terms & Inheritance Patterns Explained — CAT)
Study material on Sickle Cell Anaemia
- Sickle Cell Anaemia (1)
- Sickle Cell Anaemia
- Devendra K. Gupta, Krishna M. Goel - Hutchison’s Paediatrics. chdhe-Jaypee Brothers (2012)
- Davidson's Essentials of Medicine - 2nd
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